ArticlePLOS digital health2022
Evidence of pandemic fatigue associated with stricter tiered COVID-19 restrictions.
Article in PLOS digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed, 61 citations in OpenAlex.
- Intentional pediatric nonprescription cold/cough and analgesic/antipyretic exposure trends amid the COVID-19 pandemic.Clinical toxicology (Philadelphia, Pa.) · 2026Article
- Review
- Characterizing population-level changes in human behavior during the COVID-19 pandemic in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Mapping the intersection of demographics, behavior, and government response to the COVID-19 pandemic: an observational cohort study.BMC global and public health · 2025Article
- Preferences for Nonpharmaceutical Interventions During the Endemic Phase of COVID-19: Discrete Choice Experiment.JMIR public health and surveillance · 2025Article
- Factors affecting emerging infectious disease prevention behaviors among young workers based on ecological modeling.Scientific reports · 2025Article
- Regional variations in Italy's COVID-19 death toll: a descriptive analysis of excess mortality and associated factors from 2020 to 2021.Population health metrics · 2025Article
- Trends in the Use of Non-Pharmaceutical Interventions in Schools During the COVID-19 Pandemic, February 2021 to December 2023: A Mixed Methods Study.International journal of environmental research and public health · 2025Article
- Effect of individual preventive practices on COVID-19 infection: an analysis of big data collected at PCR testing centers in Hiroshima, Japan.BMC public health · 2025Article
- Resilience of mobility network to dynamic population response across COVID-19 interventions: Evidences from Chile.PLoS computational biology · 2025Article
- Impact of adherence and stringency on the effectiveness of lockdown measures: A modelling study.PloS one · 2025Article
- A Systematic Review of the Definition, Measurement, and Associated Factors of Pandemic Fatigue.China CDC weekly · 2024Article
- Impact of prior SARS-CoV-2 infection on college students' hesitancy to receive additional COVID-19 vaccine booster doses: A study from Taizhou, China.Preventive medicine reports · 2024Article
- Is a tiered restrictions system an effective intervention for COVID-19 control? Results from Portugal, November-December 2020.BMC public health · 2024Article
- COVID-19 control measures unexpectedly increased the duration of stay at High Speed Rail stations during the first community outbreak in Taiwan.BMC public health · 2024Article
- The end of COVID-19: not with a bang but a whimper.Irish journal of medical science · 2024Article
- The impact of spatial connectivity on NPIs effectiveness.BMC infectious diseases · 2024Article
- Heterogeneous risk tolerance, in-groups, and epidemic waves.Frontiers in applied mathematics and statistics · 2024Article
- Built environment factors moderate pandemic fatigue in social distance during the COVID-19 pandemic: A nationwide longitudinal study in the United States.Landscape and urban planning · 2023Article
- COVID-19, stigma, and habituation: evidence from mobility data.BMC public health · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the availability of effective vaccines against SARS-CoV-2, non-pharmaceutical interventions remain an important part of the effort to reduce viral circulation caused by emerging variants with the capability of evading vaccine-induced immunity. With the aim of striking a balance between effective mitigation and long-term sustainability, several governments worldwide have adopted systems of tiered interventions, of increasing stringency, that are calibrated according to periodic risk assessments. A key challenge remains in quantifying temporal changes in adherence to interventions, which can decrease over time due to pandemic fatigue, under such kind of multilevel strategies. Here, we examine whether there was a reduction in adherence to tiered restrictions that were imposed in Italy from November 2020 through May 2021, and in particular we assess whether temporal trends in adherence depended on the intensity of the restrictions adopted. We analyzed daily changes in movements and in residential time, combining mobility data with the restriction tier enforced in the Italian regions. Through mixed-effects regression models, we identified a general trend of reduction in adherence and an additional effect of faster waning associated with the most stringent tier. We estimated both effects being of the same order of magnitude, suggesting that adherence decreased twice as fast during the strictest tier as in the least stringent one. Our results provide a quantitative measure of behavioral responses to tiered interventions-a metric of pandemic fatigue-that can be integrated into mathematical models to evaluate future epidemic scenarios.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.