Evidence map›Paper›PMID 36812319›Full record

ArticleScience advances2023

Acoustic streaming enabled moderate swimming exercise reduces neurodegeneration in

Joyita Bhadra, Nakul Sridhar, Apresio Kefin Fajrial, Nia Hammond, Ding Xue, Xiaoyun Ding

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joyita BhadraDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0002-9007-6687
Nakul SridharDepartment of Mechanical Engineering, University of Colorado, 1111 Engineering Dr., Boulder, CO 80309, USA.ORCID 0000-0002-2938-3346
Apresio Kefin FajrialDepartment of Mechanical Engineering, University of Colorado, 1111 Engineering Dr., Boulder, CO 80309, USA.ORCID 0000-0001-8946-6648
Nia HammondDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0002-7120-0486
Ding XueDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0002-8429-8136
Xiaoyun DingDepartment of Mechanical Engineering, University of Colorado, 1111 Engineering Dr., Boulder, CO 80309, USA.ORCID 0000-0003-4252-9335
University of Colorado Boulder · US

Funding

Fundamental mechanisms of paternal mitochondrial eliminationand radiation-induced bystander effectsR35GM118188 · NIGMS · UNIVERSITY OF COLORADO · PI DING XUE · 2016 to 2026
$6.8M
Cell membrane disruption and recovery for intracellular deliveryR35GM142817 · NIGMS · UNIVERSITY OF COLORADO · PI DING, XIAOYUN · 2021 to 2025
$1.8M
NIGMS NIH HHS R35 GM118188NIGMS NIH HHS R35 GM142817
6 · The paper itself

Abstract

Regular physical exercise has been shown to delay and alleviate neurodegenerative diseases. Yet, optimum physical exercise conditions that provide neuronal protection and exercise-related factors remain poorly understood. Here, we create an Acoustic Gym on a chip through the surface acoustic wave (SAW) microfluidic technology to precisely control the duration and intensity of swimming exercise of model organisms. We find that precisely dosed swimming exercise enabled by acoustic streaming decreases neuronal loss in two different neurodegenerative disease models of

Indexed as

Neurodegenerative DiseasesParkinson DiseaseAcousticsAgedAnimalsCaenorhabditis elegansHumansSwimming

Identifiers

PMID36812319
PMCPMC9946341
OpenAlexW4321481439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.