ArticleProceedings of the National Academy of Sciences of the United States of America2023
Transcriptome age of individual cell types in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Network Properties Influence Covariance Between Gene Expression and Fecundity Fitness of Caenorhabditis elegans in a Novel Laboratory Environment.Genome biology and evolution · 2026Article
- Investigating Low-Temperature Stress Responses in Crustacea Aquatic Species Through Comparative Transcriptomics.Evolutionary applications · 2026Article
- A cellular basis for the hourglass pattern in vertebrate embryogenesis.Nature communications · 2026Review
- Review
- The phylotranscriptomic profile of angiosperm seed development follows a reverse hourglass pattern.The Plant cell · 2025Article
- Cell type-independent timekeeping gene modules enable embryonic stage prediction in zebrafish.bioRxiv : the preprint server for biology · 2025Article
- Evolutionary trends in the emergence of skeletal cell types.Evolution letters · 2025Article
- Decoding sexual dimorphism of the sex-shared nervous system at single-neuron resolution.Science advances · 2025Article
- Divergence in neuronal signaling pathways despite conserved neuronal identity among Caenorhabditis species.Current biology : CB · 2025Article
- Lineage-resolved analysis of embryonic gene expression evolution inScience (New York, N.Y.) · 2025Article
- A transcriptomic hourglass in brown algae.Nature · 2024Article
- oggmap: a Python package to extract gene ages per orthogroup and link them with single-cell RNA data.Bioinformatics (Oxford, England) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The phylotranscriptomic analysis of development in several species revealed the expression of older and more conserved genes in midembryonic stages and younger and more divergent genes in early and late embryonic stages, which supported the hourglass mode of development. However, previous work only studied the transcriptome age of whole embryos or embryonic sublineages, leaving the cellular basis of the hourglass pattern and the variation of transcriptome ages among cell types unexplored. By analyzing both bulk and single-cell transcriptomic data, we studied the transcriptome age of the nematode
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.