ArticleThe American journal of managed care2023
Continuity of opioid prescribing among older adults on long-term opioids.
Article in The American journal of managed care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Comparison of Opioid Utilization in Older Adults with Rheumatoid Arthritis before and after Initiating Biological or Targeted Synthetic Disease-Modifying Antirheumatic Drugs.Drugs - real world outcomes · 2026Article
- Article
- Criterion validity and divergent risk profiles of long-term opioid therapy across medicare and medicaid.PloS one · 2026Article
- The association of opioid prescribing continuity and the risk of opioid use disorder among older adults.Drug and alcohol dependence · 2025Article
- Prescription Opioid Use in Older Adults: Trends and Changes in New and Long-Term Use in the United States, 2013-2020.Drugs & aging · 2025Article
- Incidence of Opioid Dose Tapering Among Older Adults Enrolled in Medicare.Innovation in aging · 2025Article
- Opioid tapering and mental health crisis in older adults.Pharmacoepidemiology and drug safety · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectivesTo describe the continuity of opioid prescribing and prescriber characteristics among older adults with chronic noncancer pain (CNCP) who are on long-term opioid therapy (LTOT) and to evaluate the association of continuity of opioid prescribing and prescriber characteristics with the risk of opioid-related adverse events. STUDY
designNested case-control design.
methodsThis study employed a nested case-control design using a 5% random sample of the national Medicare administrative claims data for 2012-2016. Eligible individuals experiencing a composite outcome of opioid-related adverse events were defined as cases and matched to controls using incidence density sampling. Continuity of opioid prescribing (operationalized using the Continuity of Care Index) and prescriber specialty were assessed among all eligible individuals. Conditional logistic regression was conducted to assess the relationships of interest after accounting for known confounders.
resultsIndividuals with low (odds ratio [OR], 1.45; 95% CI, 1.08-1.94) and medium (OR, 1.37; 95% CI, 1.04-1.79) continuity of opioid prescribing were found to have greater odds of experiencing a composite outcome of opioid-related adverse events compared with individuals with high prescribing continuity. Fewer than 1 in 10 (9.2%) older adults starting a new LTOT episode received at least 1 prescription from a pain specialist. Receiving a prescription from a pain specialist was not significantly associated with the outcome in adjusted analyses.
conclusionsWe found that higher continuity of opioid prescribing, but not provider specialty, was significantly associated with fewer opioid-related adverse outcomes among older adults with CNCP.
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Registered trials
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