ReviewInflammopharmacology2023
The wound healing effect of botanicals and pure natural substances used in in vivo models.
Review in Inflammopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Pooled it
- Hyperforin as a Multifunctional Specialized Metabolite of Natural Origin for Chronic Diseases: From Molecular Mechanisms to Clinical Translation.Current issues in molecular biology · 2026Review
- Bioactive goldenseal (Hydrastis canadensis) fraction suppresses multidrug-resistant Pseudomonas aeruginosa in a rat burn wound model: oral and topical administration.Scientific reports · 2026Article
- Review
- Effects of Terminalia fagifolia mart. extract combined with photobiomodulation on diabetic foot ulcers: protocol for a randomized single-blind clinical trial.Lasers in medical science · 2026Article
- Wound-Healing Efficacy ofFood science & nutrition · 2026Article
- Characterization and Biological Activity of Rutin Extracted fromBiotech (Basel (Switzerland)) · 2026Article
- Quercetin in skin burn healing: mechanisms, advanced delivery systems, and translational perspectives.Frontiers in bioengineering and biotechnology · 2026Review
- Article
- Nanoparticle-based approaches for wound healing: a comprehensive review of nanomaterials enhancing tissue regeneration.Discover nano · 2025Review
- Quercetin-Loaded Graphene Oxide Nanoparticles Modulate Inflammatory Gene Expression and Enhance Cell Migration In Vitro.ChemistryOpen · 2025Article
- Fabrication of a Cellulose-Based Wound Dressing Membrane from Sugarcane Bagasse Biowaste.ACS omega · 2025Article
- Accelerated wound healing through tannin-rich Jaft extract, concentration-dependent efficacy and mechanistic insights from Quercus brantii ointment formulations.Scientific reports · 2025Article
- Mixture Containing 5% Polysaccharide Extract ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings.Gels (Basel, Switzerland) · 2025Review
- Study of the Wound-Healing Activity of a New Drug Derived from Cobalt Polyacrylate.International journal of molecular sciences · 2025Article
- "Radix Saniculae": Phytochemical Characterization and Potential Adulteration of an Austrian Traditional Wound-Healing Agent.Plants (Basel, Switzerland) · 2025Article
- Two Novel Membranes Based on Collagen and Polyphenols for Enhanced Wound Healing.International journal of molecular sciences · 2024Article
- Phytochemical Characterization and Assessment of the Wound Healing Properties of Three Eurasian Propolis.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Advancements in wound management: integrating nanotechnology and smart materials for enhanced therapeutic interventions.Discover nano · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Repairing the wound is a multistep process that includes the spatial and temporal synchronization of a different range of cell types to increase the speed of wound contraction, the proliferation of epithelial cells, and collagen formation. The need for proper management of acute wounds to be cured and not turned into chronic wounds is a significant clinical challenge. The traditional practice of medicinal plants in many regions of the world has been used in wound healing since ancient times. Recent scientific research introduced evidence of the efficacy of medicinal plants, their phyto-components, and the mechanisms underlying their wound-repairing activity. This review aims to briefly highlight the wound-curing effect of different plant extracts and purely natural substances in excision, incision, and burn experimental animal models with or without infection of mice, rats (diabetic and nondiabetic), and rabbits in the last 5 years. The in vivo studies represented reliable evidence of how powerful natural products are in healing wounds properly. They have good scavenging activity against Reactive oxygen species (ROS) and anti-inflammatory and antimicrobial effects that help in the process of wound healing. It is evident that incorporating bioactive natural products into wound dressings of bio- or synthetic polymers in nanofiber, hydrogel, film, scaffold, and sponge forms showed promising results in different phases of the wound-curing process of haemostasis, inflammation, growth, re-epithelialization, and remodelling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.