ArticlePediatric surgery international2023
Anastomotic stricture prediction in patients with esophageal atresia with distal fistula.
Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- The Use of Botulinum Toxin Type A in Esophageal Atresia Management: a Randomized, Controlled, Investigator-blinded Feasibility and Exploratory Trial in Piglets.Scientific reports · 2026Article
- Endoscopic incisional therapy for esophageal strictures in children: a retrospective cohort study.Surgical endoscopy · 2026Article
- Risk factors for anastomotic complications following thoracoscopic repair of type III esophageal atresia in neonates: a single-center retrospective cohort study.Frontiers in pediatrics · 2026Article
- Oesophageal dilatation for the anastomotic stricture post trachea-oesophageal fistula/oesophageal atresia repair.Pediatric surgery international · 2025Article
- Long-term outcomes after thoracoscopic versus open surgery for congenital esophageal atresia: propensity-score overlap weighting analysis.Pediatric surgery international · 2025Article
- Risk factors and prevention and treatment methods of anastomotic stricture after esophageal atresia repair: a literature review.Pediatric surgery international · 2025Review
- Long-gap esophageal atresia: a single center experience.Frontiers in pediatrics · 2025Article
- The role of distance between upper and lower esophageal pouches to predict the possibility of delayed repair in children with isolated esophageal atresia.Pediatric surgery international · 2023Article
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11 authors.
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Abstract
purposeTo investigate potential early risk factors for anastomotic stricture formation and assess the predictive role of post-operative esophagrams.
methodsA retrospective study of patients with esophageal atresia with distal fistula (EA/TEF) operated between 2011 and 2020. Fourteen predictive factors were tested for stricture development. Esophagrams were used to calculate early (SI1) and late (SI2) stricture index (SI = anastomosis diameter/upper pouch diameter).
resultsOf 185 patients operated for EA/TEF in the 10-year period, 169 patients met the inclusion criteria. Primary anastomosis was performed in 130 patients and delayed anastomosis in 39 patients. Stricture formed in 55 patients (33%) within 1 year from anastomosis. Four risk factors showed strong association with stricture formation in unadjusted models: long gap (p = 0.007), delayed anastomosis (p = 0.042), SI1 (p = 0.013) and SI2 (p < 0.001). A multivariate analysis showed SI1 as significantly predictive of stricture formation (p = 0.035). Cut-off values using a receiver operating characteristic (ROC) curve were 0.275 for SI1 and 0.390 for SI2. The area under the ROC curve demonstrated increasing predictiveness from SI1 (AUC 0.641) to SI2 (AUC 0.877).
conclusionsThis study identified an association between long gap and delayed anastomosis with stricture formation. Early and late stricture indices were predictive of stricture formation.
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