Evidence map›Paper›PMID 36811575›Full record

ArticleThe American journal of clinical nutrition2023

Specific botanical groups of fruit and vegetable consumption and liver cancer and chronic liver disease mortality: a prospective cohort study.

Longgang Zhao, Lina Jin, Jessica L Petrick, Hongmei Zeng, Fenglei Wang, Li Tang, Stephanie A Smith-Warner, A Heather Eliassen, Fang Fang Zhang, Peter T Campbell and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  5. Observational
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  14. Phytochemical screening ofFrontiers in nutrition · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Longgang ZhaoDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Lina JinChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Jessica L PetrickSlone Epidemiology Center, Boston University, Boston, MA, USA.
Hongmei ZengDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Fenglei WangDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Li TangDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Stephanie A Smith-WarnerDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
A Heather EliassenChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Fang Fang ZhangFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Peter T CampbellDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Edward GiovannucciDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Linda M LiaoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Katherine A McGlynnDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Susan E SteckDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Xuehong ZhangChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: xuehong.zhang@channing.harvard.edu.
Harvard University · USBrigham and Women's Hospital · USNational Cancer Institute · USUniversity of South Carolina · USAlbert Einstein College of Medicine · USBoston University · USRoswell Park Comprehensive Cancer Center · USTufts University · US

Funding

Prospective Studies of Diet and Cancer in the AARP CohortZIACP010196 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SINHA, RASHMI · 2009 to 2025
$21.0M
Helicobacter Infection and Liver Cancer Risk among African Americans andWhites in the United StatesR37CA262299 · NCI · YALE UNIVERSITY · PI Xuehong Zhang · 2021 to 2026
$2.4M
NCI NIH HHS R37 CA262299
6 · The paper itself

Abstract

backgroundBeyond alcohol and coffee, the relationship between other dietary factors, including specific vegetables and fruits, and liver outcomes remains poorly understood.

objectiveTo evaluate the associations between fruit and vegetable intake with the risk of liver cancer and chronic liver disease (CLD) mortality.

methodsThis study was based on the National Institutes of Health-American Association of Retired Persons Diet and Health Study, including 485,403 participants aged 50-71 y from 1995 to 1996. Fruit and vegetable intake was estimated using a validated food frequency questionnaire. Cox proportional hazards regression was used to estimate the multivariable hazard ratios (HR) and 95% confidence intervals (CI) for liver cancer incidence and CLD mortality.

resultsDuring a median follow-up of 15.5 y, 947 incident liver cancers and 986 CLD deaths (other than liver cancer) were confirmed. A higher intake of total vegetables was associated with a lower risk of liver cancer (HR

conclusionsHigher intakes of total vegetables, especially lettuce and cruciferous vegetables, were associated with lower liver cancer risk. Higher intakes of lettuce, sweet potatoes, cruciferous vegetables, legumes, and carrots were associated with a lower risk of CLD mortality.

Indexed as

BrassicaFabaceaeLiver NeoplasmsDietFruitHumansProspective StudiesRisk FactorsVegetablescarrotscohort studycruciferous vegetablesepidemiological studyfruitlegumeslettuceliver cancerliver disease mortalityvegetables

Identifiers

PMID36811575
PMCPMC10131619
OpenAlexW4312193594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.