Evidence map›Paper›PMID 36810749›Full record

ArticleScientific reports2023

Reirradiation for local recurrence of oral, pharyngeal, and laryngeal cancers: a multi-institutional study.

Hideya Yamazaki, Gen Suzuki, Norihiro Aibe, Hiroya Shiomi, Ryoong-Jin Oh, Ken Yoshida, Satoaki Nakamura, Koji Konishi, Mikio Ogita

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Re-irradiation in head and neck cancer: thirteen years of insights.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hideya YamazakiDepartment of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho Kawaramachi Hirokoji, Kamigyo-Ku, Kyoto, 602-8566, Japan. hideya10@hotmail.com.
Gen SuzukiDepartment of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho Kawaramachi Hirokoji, Kamigyo-Ku, Kyoto, 602-8566, Japan.
Norihiro AibeDepartment of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho Kawaramachi Hirokoji, Kamigyo-Ku, Kyoto, 602-8566, Japan.
Hiroya ShiomiCyberKnife Center, Soseikai General Hospital, Kyoto, 612-8473, Japan.
Ryoong-Jin OhDepartment of Radiation Oncology, Miyakojima IGRT Clinic, Osaka, 534-0021, Japan.
Ken YoshidaDepartment of Radiology, Kansai Medical University, Hirakata, 573-1010, Japan.
Satoaki NakamuraDepartment of Radiology, Kansai Medical University, Hirakata, 573-1010, Japan.
Koji KonishiDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.
Mikio OgitaRadiotherapy Department, Fujimoto Hayasuzu Hospital, Miyakonojo, 885-0055, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to examine the efficacy and toxicity of reirradiation in patients with locally recurrent oral, pharyngeal, and laryngeal cancers. We conducted a retrospective, multi-institutional analysis of 129 patients with previously irradiated cancer. The most frequent primary sites were the nasopharynx (43.4%), oral cavity (24.8%), and oropharynx (18.6%). With a median follow-up duration of 10.6 months, the median overall survival was 14.4 months and the 2-year overall survival rate was 40.6%. For each primary site, the 2-year overall survival rates were 32.1%, 34.6%, 30%, 60.8%, and 5.7% for the hypopharynx, oral cavity, larynx, nasopharynx, and oropharynx, respectively. Prognostic factors for overall survival were primary site (nasopharynx versus other sites) and gross tumor volume (GTV) (≤ 25 cm

Indexed as

Head and Neck NeoplasmsLaryngeal NeoplasmsRe-IrradiationHumansNeoplasm Recurrence, LocalOropharynxRetrospective Studies

Identifiers

PMID36810749
PMCPMC9944926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.