Evidence map›Paper›PMID 36810728›Full record

ArticleSignal transduction and targeted therapy2023

Mutation N856K in spike reduces fusogenicity and infectivity of Omicron BA.1.

Chunyun Sun, Huiyu Wang, Ji Yang, Desheng Kong, Yuning Chen, Haiyue Wang, Lingling Sun, Jianbo Lu, Min Teng, Liangzhi Xie

Abstract readLetter
In one paragraph

Article in Signal transduction and targeted therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Dynamic expedition of leading mutations in SARS-CoV-2 spike glycoproteins.Computational and structural biotechnology journal · 2024
    Article
  4. Article
  5. Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chunyun Sun *Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Huiyu Wang *Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Ji Yang *Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Desheng KongBeijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Yuning ChenBeijing Key Laboratory of Monoclonal Antibody Research and Development, Sino Biological Inc., Beijing, 100176, China.
Haiyue WangBeijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Lingling SunBeijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Jianbo LuBeijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China.
Min TengBeijing Key Laboratory of Monoclonal Antibody Research and Development, Sino Biological Inc., Beijing, 100176, China.
Liangzhi XieBeijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, 100176, China. LX@sinocelltech.com.ORCID 0000-0003-4504-7622

Funding

Beijing Municipal Science and Technology Commission Z211100002521026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID36810728
PMCPMC9944258

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.