Evidence map›Paper›PMID 36810558›Full record

ArticleEpigenomes2023

DNA Methylation Is a Potential Biomarker for Cardiometabolic Health in Mexican Children and Adolescents.

Abeer A Aljahdali, Jaclyn M Goodrich, Dana C Dolinoy, Hyungjin M Kim, Edward A Ruiz-Narváez, Ana Baylin, Alejandra Cantoral, Libni A Torres-Olascoaga, Martha M Téllez-Rojo, Karen E Peterson

Open access · diamondAbstract read
In one paragraph

Article in Epigenomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Abeer A AljahdaliDepartment of Clinical Nutrition, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-3104-1019
Jaclyn M GoodrichDepartment of Environmental Health Sciences, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA.ORCID 0000-0002-8289-9253
Dana C DolinoyDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
Hyungjin M KimCenter for Computing, Analytics and Research, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-0604-8027
Edward A Ruiz-NarváezDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-0339-5824
Ana BaylinDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
Alejandra CantoralDepartment of Health, Iberoamericana University, Mexico City 01219, Mexico.ORCID 0000-0002-1397-8476
Libni A Torres-OlascoagaCenter for Nutrition and Health Research, National Institute of Public Health, Cuernavaca 62100, Mexico.ORCID 0000-0002-9231-9937
Martha M Téllez-RojoCenter for Nutrition and Health Research, National Institute of Public Health, Cuernavaca 62100, Mexico.ORCID 0000-0003-3322-3334
Karen E PetersonDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-0471-1427
University of Michigan · USInstituto Nacional de Salud Pública · MXIbero American University · MXKing Abdulaziz University · SA

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson · 2010 to 2026
$20.3M
Environmental Epigenomics and Precision Environmental HealthR35ES031686 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2020 to 2026
$6.1M
Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MEEKER, JOHN D., PADMANABHAN, VASANTHA · 2013 to 2018
$3.9M
E3Gen: Multigenerational Influences of Social Structure on Toxicant Exposures and Life Course Health in the ELEMENT CohortR24ES028502 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson, Peter Xuekun Song · 2017 to 2026
$2.2M
Project 1: Prenatal Lead Exposure, Early Childhood Growth, and Sexual MaturationP20ES018171 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETERSON, KAREN EILEEN · 2010 to 2012
$584k
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIEHS NIH HHS P01 ES022844NIEHS NIH HHS P20 ES018171NIEHS NIH HHS P20 ES018171, P01 ES02284401, and R35 ES031686NIEHS NIH HHS P30 ES017885NIEHS NIH HHS R24 ES028502NIEHS NIH HHS R35 ES031686
6 · The paper itself

Abstract

DNA methylation (DNAm) is a plausible mechanism underlying cardiometabolic abnormalities, but evidence is limited among youth. This analysis included 410 offspring of the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) birth cohort followed up to two time points in late childhood/adolescence. At Time 1, DNAm was quantified in blood leukocytes at long interspersed nuclear elements (LINE-1),

Indexed as

biomarkerscardiometabolic risk factorschildren and adolescentsDNA methylationepigeneticsMexicanspopulation-based study

Identifiers

PMID36810558
PMCPMC9944859
OpenAlexW4319081357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.