Evidence map›Paper›PMID 36810541›Full record

ArticleDiseases (Basel, Switzerland)2023

"To Be or Not to Be Benign" at Partial Nephrectomy for Presumed RCC Renal Masses: Single-Center Experience with 195 Consecutive Patients.

Raffaele Baio, Giovanni Molisso, Christian Caruana, Umberto Di Mauro, Olivier Intilla, Umberto Pane, Costantino D'Angelo, Antonio Campitelli, Francesca Pentimalli, Roberto Sanseverino

Open access · goldAbstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. Article
  5. Shifting paradigms in the treatment of small renal masses.Translational andrology and urology · 2025
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Raffaele BaioDepartment of Medicine and Surgery "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-3157-0845
Giovanni MolissoDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.
Christian CaruanaDepartment of Chemistry, University of Malta, MSD2080 Msida, Malta.
Umberto Di MauroDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.
Olivier IntillaDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.
Umberto PaneDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.
Costantino D'AngeloDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Antonio CampitelliDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.
Francesca PentimalliDepartment of Medicine and Surgery, LUM University, 70010 Bari, Italy.
Roberto SanseverinoDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.
University of Malta · MTUniversity of Salerno · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In daily medical practice, an increasing number of kidney masses are being incidentally detected using common imaging techniques, owing to the improved diagnostic accuracy and increasingly frequent use of these techniques. As a consequence, the rate of detection of smaller lesions is increasing considerably. According to certain studies, following surgical treatment, up to 27% of small enhancing renal masses are identified as benign tumors at the final pathological examination. This high rate of benign tumors challenges the appropriateness of surgery for all suspicious lesions, given the morbidity associated with such an intervention. The objective of the present study was, therefore, to determine the incidence of benign tumors at partial nephrectomy (PN) for a solitary renal mass. To meet this end, a total of 195 patients who each underwent one PN for a solitary renal lesion with the intent to cure RCC were included in the final retrospective analysis. A benign neoplasm was identified in 30 of these patients. The age of the patients ranged from 29.9-79 years (average: 60.9 years). The tumor size range was 1.5-7 cm (average: 3 cm). All the operations were successful using the laparoscopic approach. The pathological results were renal oncocytoma in 26 cases, angiomyolipomas in two cases, and cysts in the remaining two cases. In conclusion, we have shown in our present series the incidence rate of benign tumors in patients who have been subjected to laparoscopic PN due to a suspected solitary renal mass. Based on these results, we advise that the patient should be counseled not only about the intra- and post-operative risks of nephron-sparing surgery but also about its dual therapeutic and diagnostic role. Therefore, the patients should be informed of the considerably high probability of a benign histological result.

Indexed as

benign renal masslaparoscopic partial nephrectomytumor size

Identifiers

PMID36810541
PMCPMC9945135
OpenAlexW4319598396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.