Evidence map›Paper›PMID 36810512›Full record

ArticleScientific reports2023

Fluorescence lifetime imaging through scattering media.

Sebastian Nilsson, Elias Kristensson, Marcus Aldén, Joakim Bood, Andreas Ehn

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastian NilssonCombustion Physics, Department of Physics, Faculty of Engineering, Lund University, Professorsgatan 1, 223 63, Lund, Sweden. sebastian.nilsson@forbrf.lth.se.
Elias KristenssonCombustion Physics, Department of Physics, Faculty of Engineering, Lund University, Professorsgatan 1, 223 63, Lund, Sweden.
Marcus AldénCombustion Physics, Department of Physics, Faculty of Engineering, Lund University, Professorsgatan 1, 223 63, Lund, Sweden.
Joakim BoodCombustion Physics, Department of Physics, Faculty of Engineering, Lund University, Professorsgatan 1, 223 63, Lund, Sweden.
Andreas EhnCombustion Physics, Department of Physics, Faculty of Engineering, Lund University, Professorsgatan 1, 223 63, Lund, Sweden.

Funding

Energimyndigheten CECOSTEuropean Commission 803634European Commission 852394Knut och Alice Wallenbergs Stiftelse 2019.0084Stiftelsen för Strategisk Forskning TM17-0309Vetenskapsrådet 2019-03601Vetenskapsrådet 2019-05183Vetenskapsrådet 2021-04506
6 · The paper itself

Abstract

Fluorescence lifetime determination has proven to be useful, e.g. identification of molecules, quantitative estimation of species concentration and determination of temperatures. Lifetime determination of exponentially decaying signals is challenging if signals of different decay rates are being mixed, resulting in erroneous results. Such issues occur when the contrast of the measurement object is low, which can be limiting in applied measurements due to spurious light scattering. A solution is presented here where structured illumination is used to enhance image contrast in fluorescence lifetime wide-field imaging. Lifetime imaging determination was carried out using Dual Imaging Modeling Evaluation (DIME), and spatial lock-in analysis was used for removing spurious scattered signal to enable fluorescence lifetime imaging through scattering media.

Identifiers

PMID36810512
PMCPMC9944959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.