Evidence map›Paper›PMID 36810480›Full record

ArticleMedical sciences (Basel, Switzerland)2023

The Importance of Mitral Valve Prolapse Doming Volume in the Assessment of Left Ventricular Stroke Volume with Cardiac MRI.

Rui Li, Hosamadin Assadi, Gareth Matthews, Zia Mehmood, Ciaran Grafton-Clarke, Bahman Kasmai, David Hewson, Richard Greenwood, Hilmar Spohr, Liang Zhong and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Aortic flow is abnormal in HFpEF.Wellcome open research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Rui LiNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
Hosamadin AssadiNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.ORCID 0000-0002-6143-8095
Gareth MatthewsNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
Zia MehmoodNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
Ciaran Grafton-ClarkeNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
Bahman KasmaiNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
David HewsonNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
Richard GreenwoodNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
Hilmar SpohrNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
Liang ZhongNational Heart Research Institute Singapore, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609, Singapore.
Xiaodan ZhaoNational Heart Research Institute Singapore, National Heart Centre Singapore, 5 Hospital Drive, Singapore 169609, Singapore.
Chris SawhNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
Rudolf DuehmkeCardiology Department, Queen Elizabeth Hospital King's Lynn NHS Foundation Trust, King's Lynn PE30 4ET, UK.
Vassilios S VassiliouNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.ORCID 0000-0002-4005-7752
Faye NelthorpeNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
David AshmanNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
John CurtinNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
Gurung-Koney YashodaNorfolk and Norwich University Hospitals NHS Foundation Trust, Norfolk NR4 7UY, UK.
Rob J Van der GeestDepartment of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-9084-5597
Samer AlabedDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK.
Andrew J SwiftDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK.
Marina HughesNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.
Pankaj GargNorwich Medical School, University of East Anglia, Norfolk NR4 7TJ, UK.ORCID 0000-0002-5483-169X

Funding

Wellcome Trust 205188/Z/16/ZWellcome Trust 220703/Z/20/Z
6 · The paper itself

Abstract

There remains a debate whether the ventricular volume within prolapsing mitral valve (MV) leaflets should be included in the left ventricular (LV) end-systolic volume, and therefore factored in LV stroke volume (SV), in cardiac magnetic resonance (CMR) assessments. This study aims to compare LV volumes during end-systolic phases, with and without the inclusion of the volume of blood on the left atrial aspect of the atrioventricular groove but still within the MV prolapsing leaflets, against the reference LV SV by four-dimensional flow (4DF). A total of 15 patients with MV prolapse (MVP) were retrospectively enrolled in this study. We compared LV SV with (LV SV

Indexed as

Mitral Valve ProlapseHumansMagnetic Resonance ImagingRetrospective StudiesStroke VolumeVentricular Function, LeftAIflow quantificationmitral valve prolapsereliability

Identifiers

PMID36810480
PMCPMC9945133

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.