Evidence map›Paper›PMID 36810412›Full record

ReviewBiomimetics (Basel, Switzerland)2023

A Review on Manufacturing Processes of Biocomposites Based on Poly(α-Esters) and Bioactive Glass Fillers for Bone Regeneration.

Xavier Lacambra-Andreu, Abderrahim Maazouz, Khalid Lamnawar, Jean-Marc Chenal

Abstract readReview
In one paragraph

Review in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xavier Lacambra-AndreuCNRS, UMR 5223, Ingénierie des Matériaux Polymères, INSA Lyon, Université de Lyon, F-69621 Villeurbanne, France.
Abderrahim MaazouzCNRS, UMR 5223, Ingénierie des Matériaux Polymères, INSA Lyon, Université de Lyon, F-69621 Villeurbanne, France.ORCID 0000-0002-2961-5872
Khalid LamnawarCNRS, UMR 5223, Ingénierie des Matériaux Polymères, INSA Lyon, Université de Lyon, F-69621 Villeurbanne, France.ORCID 0000-0003-4907-0977
Jean-Marc ChenalCNRS, UMR 5510, MATEIS, INSA-Lyon, Université de Lyon, F-69621 Villeurbanne, France.

Funding

French Ministry of Higher Education and Research (MESRI) DRH/2019/09/681
6 · The paper itself

Abstract

The incorporation of bioactive and biocompatible fillers improve the bone cell adhesion, proliferation and differentiation, thus facilitating new bone tissue formation upon implantation. During these last 20 years, those biocomposites have been explored for making complex geometry devices likes screws or 3D porous scaffolds for the repair of bone defects. This review provides an overview of the current development of manufacturing process with synthetic biodegradable poly(α-ester)s reinforced with bioactive fillers for bone tissue engineering applications. Firstly, the properties of poly(α-ester), bioactive fillers, as well as their composites will be defined. Then, the different works based on these biocomposites will be classified according to their manufacturing process. New processing techniques, particularly additive manufacturing processes, open up a new range of possibilities. These techniques have shown the possibility to customize bone implants for each patient and even create scaffolds with a complex structure similar to bone. At the end of this manuscript, a contextualization exercise will be performed to identify the main issues of process/resorbable biocomposites combination identified in the literature and especially for resorbable load-bearing applications.

Indexed as

bioglassmanufacturing processmechanical propertiesPLA

Identifiers

PMID36810412
PMCPMC9945144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.