Evidence map›Paper›PMID 36810408›Full record

ArticleBiomimetics (Basel, Switzerland)2023

Biomimetic Material for Quantification of Methotrexate Using Sensor Based on Molecularly Imprinted Polypyrrole Film and MWCNT/GCE.

Eduardo Jara-Cornejo, Sabir Khan, Jaime Vega-Chacón, Ademar Wong, Lariel Chagas da Silva Neres, Gino Picasso, Maria D P T Sotomayor

Open access · goldAbstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Alphabet of Nanostructured Polypyrrole.Materials (Basel, Switzerland) · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Eduardo Jara-CornejoLaboratory of Physical Chemistry Research, Faculty of Sciences, National University of Engineering, Av. Tupac Amaru 210, Lima 15333, Peru.ORCID 0000-0002-4504-4176
Sabir KhanLaboratory of Physical Chemistry Research, Faculty of Sciences, National University of Engineering, Av. Tupac Amaru 210, Lima 15333, Peru.ORCID 0000-0003-4557-238X
Jaime Vega-ChacónLaboratory of Physical Chemistry Research, Faculty of Sciences, National University of Engineering, Av. Tupac Amaru 210, Lima 15333, Peru.ORCID 0000-0002-8011-458X
Ademar WongInstitute of Chemistry, São Paulo State University (UNESP), Araraquara 14801-970, Brazil.
Lariel Chagas da Silva NeresInstitute of Chemistry, São Paulo State University (UNESP), Araraquara 14801-970, Brazil.
Gino PicassoLaboratory of Physical Chemistry Research, Faculty of Sciences, National University of Engineering, Av. Tupac Amaru 210, Lima 15333, Peru.ORCID 0000-0002-5553-5278
Maria D P T SotomayorInstitute of Chemistry, São Paulo State University (UNESP), Araraquara 14801-970, Brazil.ORCID 0000-0002-6173-7888
National University of Engineering · PEUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal Rural do Semi-Árido · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates biomimetic sensors for the detection of methotrexate contaminants in environmental samples. Sensors inspired by biological systems are the focus of this biomimetic strategy. Methotrexate is an antimetabolite that is widely used for the treatment of cancer and autoimmune diseases. Due to the widespread use of methotrexate and its rampant disposal into the environment, the residues of this drug are regarded as an emerging contaminant of huge concern, considering that exposure to the contaminant has been found to lead to the inhibition of some essential metabolic processes, posing serious risks to humans and other living beings. In this context, this work aims to quantify methotrexate through the application of a highly efficient biomimetic electrochemical sensor constructed using polypyrrole-based molecularly imprinted polymer (MIP) electrodeposited by cyclic voltammetry on a glassy carbon electrode (GCE) modified with multi-walled carbon nanotubes (MWCNT). The electrodeposited polymeric films were characterized by infrared spectrometry (FTIR), scanning electron microscopy (SEM), and cyclic voltammetry (CV). The analyses conducted using differential pulse voltammetry (DPV) yielded a detection limit of 2.7 × 10

Indexed as

biomimetic sensorselectropolymerizationmethotrexatemolecularly imprinted polymerMWCNTpolypyrrolesensor film

Identifiers

PMID36810408
PMCPMC9944472
OpenAlexW4320490701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.