ReviewBiomimetics (Basel, Switzerland)2023
Heterogeneous Nucleation in Protein Crystallization.
Review in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Investigating the Effects of Nanogels in Promoting Protein Crystallization.International journal of molecular sciences · 2026Article
- Alternative Strategies to Promote Biomolecule Nucleation.Advances in biochemical engineering/biotechnology · 2026Review
- Learn from nature: Biomimetic nanocarriers for intracellular protein delivery.Bioactive materials · 2026Review
- A multiscaleJournal of applied crystallography · 2025Article
- Facile Fabrication of Large-Area and High-Quality Organic-Inorganic Hybrid Perovskite Ferroelectric Films Through Electrohydrodynamic Printing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Crowding and in-Cell Crystallization.Sub-cellular biochemistry · 2025Review
- Increasing the Particle Size and Magnetic Property of Iron Oxide Nanoparticles through a Segregated Nucleation and Growth Process.Nanomaterials (Basel, Switzerland) · 2024Article
- Unraveling the association of bacteria and urinary stones in patients with urolithiasis: an update review article.Frontiers in medicine · 2024Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Protein crystallization was first discovered in the nineteenth century and has been studied for nearly 200 years. Protein crystallization technology has recently been widely used in many fields, such as drug purification and protein structure analysis. The key to successful crystallization of proteins is the nucleation in the protein solution, which can be influenced by many factors, such as the precipitating agent, temperature, solution concentration, pH, etc., among which the role of the precipitating agent is extremely important. In this regard, we summarize the nucleation theory of protein crystallization, including classical nucleation theory, two-step nucleation theory, and heterogeneous nucleation theory. We focus on a variety of efficient heterogeneous nucleating agents and crystallization methods as well. The application of protein crystals in crystallography and biopharmaceutical fields is further discussed. Finally, the bottleneck of protein crystallization and the prospect of future technology development are reviewed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.