Evidence map›Paper›PMID 36810376›Full record

ReviewBiomimetics (Basel, Switzerland)2023

Clinical Use of Non-Suture Silk-Containing Products: A Systematic Review.

Jose A Foppiani, Allan Weidman, Angelica Hernandez Alvarez, Lauren Valentine, Karthika Devi, David L Kaplan, Samuel J Lin

Open access · goldAbstract readReview
In one paragraph

Review in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jose A FoppianiDivision of Plastic Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Allan WeidmanDivision of Plastic Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Angelica Hernandez AlvarezDivision of Plastic Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Lauren ValentineDivision of Plastic Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.ORCID 0000-0001-5762-5253
Karthika DeviSri Manakula Vinayagar Medical College, Pondicherry University, Puducherry 605107, India.
David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.ORCID 0000-0002-9245-7774
Samuel J LinDivision of Plastic Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Beth Israel Deaconess Medical Center · USPondicherry University · INTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe purpose of this systematic review is to determine how various innovative non-suture silk and silk-containing products are being used in clinical practice, and compare patient outcomes following their use.

methodsA systematic review of PubMed, Web of Science, and Cochrane was completed. A qualitative synthesis of all included studies was then performed.

resultsOur electronic search identified 868 silk-related publications, which yielded 32 studies for full-text review. After exclusion, nine studies from 2011 to 2018 were included for qualitative analysis. A total of 346 patients were included which consisted of 37 males and 309 females. The mean age range was between 18-79 years old. The follow-up among studies ranged between one to twenty-nine months. Three studies addressed the application of silk in wound dressings, one on the topical application of silk-derived products, one on silk-derived scaffold in breast reconstruction, and three on silk underwear as adjunct for the treatment of gynecological conditions. All studies showed good outcomes alone or in comparison to controls.

conclusionThis systematic review concludes that silk products' structural, immune, and wound-healing modulating properties are advantageous clinical assets. Nevertheless, more studies are needed to strengthen and establish the benefit of those products.

Indexed as

bioinspirationbiomimeticsbiomimetics in tissue regenerationbiopolymersclinical utilitysilksilk biomaterialssilk-derivedsystematic review

Identifiers

PMID36810376
PMCPMC9944446
OpenAlexW4317433984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.