The Differential Contribution of Macular Pigments and Foveal Anatomy to the Perception of Maxwell's Spot and Haidinger's Brushes.

Gary P Misson, Rebekka Heitmar, Richard Armstrong, Stephen J Anderson

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Article in Vision (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gary P MissonSchool of Optometry, College of Health & Life Sciences, Aston University, Birmingham B4 7ET, UK.ORCID 0000-0001-8843-8389

Rebekka HeitmarDepartment of Optometry and Vision Sciences, Centre for Vision across the Life Span, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.ORCID 0000-0002-7657-1788

Richard ArmstrongSchool of Optometry, College of Health & Life Sciences, Aston University, Birmingham B4 7ET, UK.

Stephen J AndersonSchool of Optometry, College of Health & Life Sciences, Aston University, Birmingham B4 7ET, UK.ORCID 0000-0002-5719-2846

Aston University · GBUniversity of Huddersfield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship of macular pigments and foveal anatomy to the perception of Maxwell's spot (MS) and Haidinger's brushes (HB) entoptic phenomena were investigated. Dual-wavelength-autofluorescence and OCT were used to define macular pigment density and foveal anatomy in 52 eyes. MS was generated by alternating unpolarized red/blue and red/green uniform field illumination. HB was generated by alternating the linear polarization axis of a uniform blue field. In Experiment 1, horizontal widths of MS and HB were measured using a micrometer system and compared with macular pigment densities and OCT-defined morphometry. MS radius (mean 1.4°) was significantly less than HB radius (mean 1.6°), with the spatial extent of both phenomena falling between the boundaries of the foveola and foveal pit. Multiple regression showed MS and HB radii to be significantly associated with the macular pigment spatial profile radius. HB radius, but not MS radius, was also significantly associated with foveolar morphometry. Experiment 2 compared perceptual profiles of MS with macular pigment distribution patterns and demonstrated close agreement. The size and appearance of MS is a direct indicator of macular pigment density and distribution. Measures of HB radii are less specific, with dependence on both macular pigment density and foveal structure.

Indexed as

central visionentoptic phenomenafoveaHaidinger’s brushesmaculamacular pigmentMaxwell’s spotpolarized light

Identifiers

PMID36810315

DOI10.3390/vision7010011

PMCPMC9944110

OpenAlexW4319440078

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.