Evidence map›Paper›PMID 36810286›Full record

ArticleEcho research and practice2023

The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation.

Mark Coyle, Gerard King, Kathleen Bennett, Andrew Maree, Mark Hensey, Stephen O'Connor, Caroline Daly, Gregory Murphy, Ross T Murphy

Abstract read
In one paragraph

Article in Echo research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mark CoyleDepartment of Cardiology, St James Hospital, Dublin, Ireland. Markcoyle95@gmail.com.
Gerard KingDepartment of Cardiology, St James Hospital, Dublin, Ireland.
Kathleen BennettSchool of Population Health, Royal College of Surgeons Ireland, University of Medicine and Health, Dublin, Ireland.
Andrew MareeDepartment of Cardiology, St James Hospital, Dublin, Ireland.
Mark HenseyDepartment of Cardiology, St James Hospital, Dublin, Ireland.
Stephen O'ConnorDepartment of Cardiology, St James Hospital, Dublin, Ireland.
Caroline DalyDepartment of Cardiology, St James Hospital, Dublin, Ireland.
Gregory MurphyDepartment of Cardiology, St James Hospital, Dublin, Ireland.
Ross T MurphyDepartment of Cardiology, St James Hospital, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeformation imaging represents a method of measuring myocardial function, including global longitudinal strain (GLS), peak atrial longitudinal strain (PALS) and radial strain. This study aimed to assess subclinical improvements in left ventricular function in patients undergoing transcatheter aortic valve implantation (TAVI) by comparing GLS, PALS and radial strain pre and post procedure.

methodsWe conducted a single site prospective observational study of 25 patients undergoing TAVI, comparing baseline and post-TAVI echocardiograms. Individual participants were assessed for differences in GLS, PALS and radial strain in addition to changes in left ventricular ejection fraction (LVEF) (%).

resultsOur results revealed a significant improvement in GLS (mean change pre-post of 2.14% [95% CI 1.08, 3.20] p = 0.0003) with no significant change in LVEF (0.96% [95% CI - 2.30, 4.22], p = 0.55). There was a statistically significant improvement in radial strain pre and post TAVI (mean 9.68% [95% CI 3.10, 16.25] p = 0.0058). There was positive trend towards improvements in PALS pre and post TAVI (mean change of 2.30% [95% CI - 0.19, 4.80] p = 0.068).

conclusionIn patients undergoing TAVI, measuring GLS and radial strain provided statistically significant information regarding subclinical improvements in LV function, which may have prognostic implications. The incorporation of deformation imaging in addition to standard echocardiographic measurements may have an important role in guiding future management in patients undergoing TAVI and assessing response.

Indexed as

Aortic stenosisHeart failureLV strainReduced ejection fractionTAVIValve disease

Identifiers

PMID36810286
PMCPMC9945603

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.