Evidence map›Paper›PMID 36810170›Full record

ArticleBMJ open2023

Long COVID symptoms in Israeli children with and without a history of SARS-CoV-2 infection: a cross-sectional study.

Limor Adler, Moran Israel, Ilan Yehoshua, Joseph Azuri, Robert Hoffman, Arnon Shahar, Miri Mizrahi Reuveni, Zachi Grossman

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Understanding how social determinants of health shape Long COVID outcomes: a rapid review of evidence.Archives of public health = Archives belges de sante publique · 2025
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  6. A Predictive Model for the Development of Long COVID in Children.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Limor AdlerDepartment of Family Medicine, Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel adler_l@mac.org.il.ORCID 0000-0002-9335-6596
Moran IsraelHealth Division, Maccabi Healthcare Services, Tel Aviv, Israel.
Ilan YehoshuaHealth Division, Maccabi Healthcare Services, Tel Aviv, Israel.
Joseph AzuriDepartment of Family Medicine, Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel.
Robert HoffmanDepartment of Family Medicine, Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel.ORCID 0000-0002-3053-835X
Arnon ShaharHealth Division, Maccabi Healthcare Services, Tel Aviv, Israel.
Miri Mizrahi ReuveniHealth Division, Maccabi Healthcare Services, Tel Aviv, Israel.
Zachi GrossmanHealth Division, Maccabi Healthcare Services, Tel Aviv, Israel.
Tel Aviv University · ILBen-Gurion University of the Negev · ILFaculty (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate the prevalence of long COVID symptoms in children with and without a history of SARS-CoV-2 infection and to evaluate factors associated with long COVID.

designA nationwide cross-sectional study.

settingPrimary care.

participants3240 parents of children aged 5-18 with and without SARS-CoV-2 infection completed an online questionnaire (11.9% response rate); 1148 and 2092 with/without a history of infection, respectively. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome was the prevalence of long COVID symptoms in children with/without a history of infection. Secondary outcomes were the factors associated with the presence of long COVID symptoms and with failure to return to baseline health status in children with a history of infection including gender, age, time from illness, symptomatic illness and vaccine status.

resultsMost long COVID symptoms were more prevalent in children with a history of SARS-CoV-2 infection: headaches (211 (18.4%) vs 114 (5.4%), p<0.001), weakness (173 (15.1%) vs 70 (3.3%), p<0.001), fatigue (141 (12.3%) vs 133 (6.4%), p<0.001) and abdominal pain (109 (9.5%) vs 79 (3.8%), p<0.001). Most long COVID symptoms in children with a history of SARS-CoV-2 infection were more prevalent in the older age group (12-18) compared with the younger age group (5-11). Some symptoms were more prevalent in children without a history of SARS-CoV-2 infection, including attention problems with school malfunctioning (225 (10.8%) vs 98 (8.5%), p=0.05), stress (190 (9.1%) vs 65 (5.7%), p<0.001), social problems (164 (7.8%) vs 32 (2.8%)) and weight changes (143 (6.8%) vs 43 (3.7%), p<0.001).

conclusionThis study suggests that the prevalence of long COVID symptoms in children with a history of SARS-CoV-2 infection might be higher and more prevalent in adolescents than in young children. Some of the symptoms, mainly somatic symptoms, were more prevalent in children without a history of SARS-CoV-2 infection, highlighting the impact of the pandemic itself rather than the infection.

Indexed as

COVID-19Post-Acute COVID-19 SyndromeAdolescentAgedChildChild, PreschoolCross-Sectional StudiesHumansIsraelSARS-CoV-2COVID-19EPIDEMIOLOGYPAEDIATRICSPRIMARY CARE

Identifiers

PMID36810170
PMCPMC9944622
OpenAlexW4321452025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.