ArticleBMC musculoskeletal disorders2023
Application of antibiotic bone cement in the treatment of infected diabetic foot ulcers in type 2 diabetes.
Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Local Versus Systemic Antibiotics for Diabetic Foot Infection-A Systematic Review and Meta-Analysis.Journal of diabetes · 2026Pooled it
- The efficacy of three antimicrobial dressings in the management of diabetic foot ulcers: a systematic review and network meta-analysis.Frontiers in endocrinology · 2026Pooled it
- PMMA-induced membranous angiogenesis accelerates wound healing in refractory diabetic foot ulcers: A comparative cohort study.JPRAS open · 2026Article
- [Expert consensus on the application of bone cement in the treatment of diabetic wounds (2026 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Long-Term Clinical and Radiologic Evaluation of Micronized Acellular Dermal Matrix-Assisted Reconstruction in Diabetes-Related and Traumatic Foot Wounds With Bone Defects.International wound journal · 2026Article
- [Clinical effects of antibiotic bone cement and VSD combined with free chimeric anterolateral thigh perforator myocutaneous flaps for sequential treatment of diabetic calcaneal osteomyelitis wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- [Mechanism of actions and reflections of Masquelet induced membrane technique in diabetic wound].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Review
- Evaluation of wound regeneration potential of nano-phytoextracts loaded carboxymethyl chitosan scaffolds for diabetic foot ulcer.Scientific reports · 2025Article
- [Research on the pathogenesis and treatment of diabetic foot ulcer wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025Review
- Does preoperative muscle biopsy predict the outcome of lower extremity amputation in diabetic patients? a prospective observational study.BMC musculoskeletal disorders · 2025Observational
- Boruta algorithm-guided antibiotic selection in antibiotic-loaded bone cement for diabetic foot ulcers: microbiota and susceptibility analysis.Frontiers in pharmacology · 2025Article
- Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- A three-stage sequential surgical approach to a more efficient management of clinical stage 4 diabetic foot ulcers.Frontiers in surgery · 2025Article
- Adjuvant local antibiotic therapy in the management of diabetic foot osteomyelitis.Clinical diabetes and endocrinology · 2024Article
- Revisiting Antibiotic-Impregnated Cement Spacer for Diabetic Osteomyelitis of the Foot.Antibiotics (Basel, Switzerland) · 2024Article
- Application of antibiotic bone cement combined with lobulated perforator flap based on descending branch of the lateral circumflex femoral artery in treatment of infected traumatic tissue defects of foot.BMC musculoskeletal disorders · 2024Article
- Combining antibiotic-loaded bone cement-based free vastus lateralis muscle-sparing flap with split-thickness skin grafts: A reliable strategy for reconstructing diabetic foot ulcers at non-weight-bearing areas.International wound journal · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIn this study, we try to investigate the effect of antibiotic bone cement in patients with infected diabetic foot ulcer (DFU).
methodsThis is a retrospective study, including fifty-two patients with infected DFU who had undergone treated between June 2019 and May 2021. Patients were divided into Polymethylmethacrylate (PMMA) group and control group. 22 patients in PMMA group received antibiotic bone cement and regular wound debridement, and 30 patients in control group received regular wound debridement. Clinical outcomes include the rate of wound healing, duration of healing, duration of wound preparation, rate of amputation, and frequency of debridement procedures.
resultsIn PMMA group, twenty-two patients (100%) had complete wound healing. In control group, twenty-eight patients (93.3%) had wound healing. Compared with control group, PMMA group had fewer frequencies of debridement procedures and shorter duration of wound healing (35.32 ± 3.77 days vs 44.37 ± 7.44 days, P < 0.001). PMMA group had five minor amputation, while control group had eight minor amputation and two major amputation. Regarding the rate of limb salvage, there was no limb lose in PMMA group and two limb losses in control group.
conclusionThe application of antibiotic bone cement is an effective solution for infected DFU treatment. It can effectively decreased the frequency of debridement procedures and shorten the healing duration in patients with infected DFU.
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