ArticleThe journal of headache and pain2023
Alteration of the cortical morphology in classical trigeminal neuralgia: voxel-, deformation-, and surface-based analysis.
Article in The journal of headache and pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Tuina Alleviates Pain Associated with Lumbar Disc Herniation by Regulating Functional Connectivity Between Inferior Frontal Triangularis and Multiple Brain Networks: A Randomized Controlled fMRI Study.Journal of pain research · 2026Trial
- Brain Regional Predictors of Surgical Response Are Dynamically Associated with Post-Surgical Pain Relief in Trigeminal Neuralgia.Brain sciences · 2026Article
- Neurovascular Compression Syndromes of Cranial Nerves: A Multidisciplinary Guide to Management.Brain sciences · 2026Review
- Research Progress on Radiofrequency Treatment of Primary Trigeminal Neuralgia in the V2 Maxillary Nerve.Pain and therapy · 2026Review
- No Glymphatic Dysfunction in Trigeminal Neuralgia: A Preliminary Study.Brain and behavior · 2026Article
- Subcortical neuroimaging signature of painful disorders of the trigeminal nerve: a UK Biobank study.The journal of headache and pain · 2026Article
- Abnormal Regional Brain Functional Activity and Brain Network Connectivity in Primary Trigeminal Neuralgia Patients: An Activation Likelihood Estimation Meta-Analysis Based on Resting-State fMRI.Journal of pain research · 2026Review
- Altered gray matter morphometry in psychogenic erectile dysfunction patients: A Surface-based morphometry study.Scientific reports · 2025Article
- Structural alterations in occipital cortices in trigeminal neuralgia: a voxel- and surface-based morphometric MRI study.The journal of headache and pain · 2025Article
- Glymphatic and neurofluidic dysfunction in classical trigeminal neuralgia: a multimodal MRI study of brain-CSF functional and structural dynamics.BMC medical imaging · 2025Article
- Thalamic changes in patients with chronic facial pain.Neuroradiology · 2025Article
- Decoding pain chronification: mechanisms of the acute-to-chronic transition.Frontiers in molecular neuroscience · 2025Review
- Cortical Morphology Alterations Mediate the Relationship Between Glymphatic System Function and the Severity of Asthenopia.International journal of biomedical imaging · 2025Article
- Trigeminal neuralgia caused by venous compression: a comprehensive literature review.Journal of medicine and life · 2024Review
- Altered trends of local brain function in classical trigeminal neuralgia patients after a single trigger pain.BMC medical imaging · 2024Article
- Article
- The white matter characteristic of the genu of corpus callosum coupled with pain intensity and negative emotion scores in patients with trigeminal neuralgia: a multivariate analysis.Frontiers in neuroscience · 2024Article
- A combined radiomics and anatomical features model enhances MRI-based recognition of symptomatic nerves in primary trigeminal neuralgia.Frontiers in neuroscience · 2024Article
- Brain entropy changes in classical trigeminal neuralgia.Frontiers in neurology · 2023Article
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Authors and funding
10 authors.
Funding
Abstract
objectiveThis study aimed to combine voxel-based morphometry, deformation-based morphometry, and surface-based morphometry to analyze gray matter volume and cortex shape in classical trigeminal neuralgia patients.
methodsThis study included 79 classical trigeminal neuralgia patients and age- and sex-matched 81 healthy controls. The aforementioned three methods were used to analyze brain structure in classical trigeminal neuralgia patients. Spearman correlation analysis was used to analyze the correlation of brain structure with the trigeminal nerve and clinical parameters.
resultsThe bilateral trigeminal nerve was atrophied, and the ipsilateral trigeminal nerve volume was smaller than the contralateral volume in the classical trigeminal neuralgia. The gray matter volume of Temporal_Pole_Sup_R and Precentral_R was found to be decreased using voxel-based morphometry. The gray matter volume of Temporal_Pole_Sup_R had a positive correlation with disease duration and a negative correlation with the cross-section area of the compression point and the quality-of-life score in trigeminal neuralgia. The gray matter volume of Precentral_R was negatively correlated with the ipsilateral volume of the trigeminal nerve cisternal segment, cross-section area of compression point, and visual analogue scale. The gray matter volume of Temporal_Pole_Sup_L was found to be increased using deformation-based morphometry and had a negative correlation with the self-rating anxiety scale. The gyrification of the middle temporal gyrus_L increased and the Postcentral_L thickness decreased, as detected using surface-based morphometry.
conclusionsThe gray matter volume and cortical morphology of pain-related brain regions were correlated with clinical and trigeminal nerve parameters. voxel-based morphometry, deformation-based morphometry, and surface-based morphometry complemented each other in analyzing the brain structures of patients with classical trigeminal neuralgia and provided a basis for studying the pathophysiology of classical trigeminal neuralgia.
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