Evidence map›Paper›PMID 36809658›Full record

ArticleJournal of endocrinological investigation2023

Efficacy, feasibility and tolerability of ketogenic diet for the treatment of poor response to bariatric surgery.

F Vinciguerra, S Longhitano, N Carrubba, L Piazza, C Di Stefano, M L Arpi, R Baratta, M Hagnäs, L Frittitta

Open access · hybridAbstract read
In one paragraph

Article in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

F VinciguerraDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy. vinciguerrafederica@gmail.com.ORCID http://orcid.org/0000-0001-9916-4272
S LonghitanoDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
N CarrubbaDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
L PiazzaGeneral and Emergency Surgery Department, Garibaldi Hospital, Catania, Italy.
C Di StefanoGeneral and Emergency Surgery Department, Garibaldi Hospital, Catania, Italy.
M L ArpiEndocrinology Unit: Garibaldi Hospital, Catania, Italy.
R BarattaEndocrinology Unit: Garibaldi Hospital, Catania, Italy.
M HagnäsRovaniemi Health Center, Rovaniemi and Primary Health Care Unit, Lapland Central Hospital, Rovaniemi, Finland.
L FrittittaDepartment of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Ospedale Garibaldi · ITUniversity of Catania · ITOulu University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePoor response to bariatric surgery, namely insufficient weight loss (IWL) or weight regain (WR), is a critical issue in the treatment of obesity. The purpose of our study was to assess the efficacy, feasibility, and tolerability of very low-calorie ketogenic diet (VLCKD) for the management of this condition.

methodsA real-life prospective study was conducted on twenty-two patients who experienced poor response after bariatric surgery and followed a structured VLCKD. Anthropometric parameters, body composition, muscular strength, biochemical analyses, and nutritional behavior questionnaires were evaluated.

resultsA significant weight loss (mean 14.1 ± 4.8%), mostly due to fat mass, was observed during VLCKD with the preservation of muscular strength. The weight loss obtained allowed patients with IWL to reach a body weight significantly lower than that obtained at the post-bariatric surgery nadir and to report the body weight of patients with WR at the nadir observed after surgery. The significantly beneficial changes in nutritional behaviors and metabolic profiles were observed without variations in kidney and liver function, vitamins, and iron status. The nutritional regimen was well tolerated, and no significant side effects were detected.

conclusionOur data demonstrate the efficacy, feasibility, and tolerability of VLCKD in patients with poor response after bariatric surgery.

Indexed as

Bariatric SurgeryDiet, KetogenicFeasibility StudiesHumansObesityProspective StudiesWeight LossBariatric surgeryInsufficient weight lossPoor responseVery-low-calorie ketogenic dietWeight regain

Identifiers

PMID36809658
PMCPMC10371952
OpenAlexW4321437485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.