ArticleOphthalmology and therapy2023
Safety and Efficacy of Double Lamellar Keratoplasty for Corneal Perforation.
Article in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 0 citations in OpenAlex.
- Etiology, surgical management, and outcomes of patients with scleral thinning.The Journal of international medical research · 2026Observational
- Amniotic membrane transplantation combined with cryotherapy vs. lamellar keratoplasty for medically refractory peripheral ulcerative keratitis: a retrospective cohort study.Frontiers in medicine · 2026Article
- A multicenter retrospective study of non-traumatic corneal perforation: etiology, disease course, clinical manifestations, and treatment strategies.International journal of ophthalmology · 2026Article
- Retrospective Evaluation of Successive BiovanceClinical ophthalmology (Auckland, N.Z.) · 2026Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
introductionTo assess the outcomes of double lamellar keratoplasty in the treatment of corneal perforation secondary to various keratopathies.
methodsIn this prospective non-comparative interventional case series, 15 eyes from 15 consecutive patients with corneal perforation were chosen to undergo double lamellar keratoplasty, which is characterized by two layers of lamellar grafting in the perforated area. The posterior graft was separated from a relatively healthy and thin lamellar graft of the recipient, and the anterior graft was transplanted from the donor lamellar cornea. Preoperative characteristics and postoperative examination and relevant complications throughout the study were recorded.
resultsNine men and six women with an average age of 50.73 ± 19.89 (range, 9-84) years were enrolled. The median follow-up period was 18 (range, 12-30) months. In all postoperative patients, the integrity of the eyeball was successfully rebuilt, and the anterior chambers were formed without aqueous leakage. At the last visit, best-corrected visual acuity improved in 14/15 patients (93.3%). Slit-lamp microscopy showed that all treated eyes remained fully transparent. Anterior segment optical coherence tomography revealed that the double-layer structure of the treated cornea was clear in the early postoperative stage. In vivo confocal microscopy revealed intact epithelial cells, sub-basal nerves, and clear keratocytes in the transplanted cornea. No immune rejection or recurrence was detected during the follow-up period.
conclusionsDouble lamellar keratoplasty presents a new therapeutic option for patients undergoing corneal perforation, and it provides improvement in visual acuity and reduces the risk of postoperative adverse events.
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