ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Examining the psychometric properties of a split version of the EQ-5D-5L anxiety/depression dimension in patients with anxiety and/or depression.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluating health-related quality of life in Ethiopia: systematic review and meta-analysis of EQ-5D-based studies.Frontiers in epidemiology · 2024Pooled it
- Comparative performance of the EQ-5D-5L, EQ-HWB, and PROMIS-10 in screening for history of anxiety and depression in the general adult population in 15 countries.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- The psychometric performance of the EQ-5D-5L composite and component items in the U.S. General population and by age group.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Health-Related Quality of Life in Survivors of Stroke Post Inpatient Rehabilitation Discharged to a Home Setting.Archives of rehabilitation research and clinical translation · 2025Article
- Letter to the editor concerning "Anxiety and depression 1-year after spinal tumor surgery: a retrospective analysis of psychological and clinical predictors" by R.Z. Ahmed, et al. (Eur spine J [2025]; doi: 10.1007/s00586-025-09325-7).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Appropriateness of the EQ-HWB for Use in Residential Aged Care: A Proxy Perspective.The patient · 2024Article
- The performance relationship between the EQ-5D-5L composite "Anxiety/Depression" dimension and anxiety and depression symptoms in a large, general population sample.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Health-related quality of life and utility values among patients with anxiety and/or depression in a low-income tertiary care setting: a cross-sectional analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Face Validity of Four Preference-Weighted Quality-of-Life Measures in Residential Aged Care: A Think-Aloud Study.The patient · 2023Article
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Abstract
purposeThis study explored differences in self-reported responses and the psychometric performance of the composite EQ-5D-5L anxiety/depression (A/D) dimension compared with a split version of the dimension where 'anxiety' and 'depression' are measured separately.
methodsPeople with anxiety and/or depression who visited the Amanuel Mental Specialized Hospital in Ethiopia completed the standard EQ-5D-5L with the added subdimensions. Correlation analysis was used to examine convergent validity with validated measures of depression (PHQ-9) and anxiety (GAD-7), while ANOVA was used to assess known-groups' validity. Agreement between ratings for composite and split dimensions was compared using percent agreement and Cohen's Kappa, while the proportion of 'no problems' reports was compared using the chi-square test. Discriminatory power analysis was undertaken using the Shannon index (H') and Shannon Evenness index (J'). Open-ended questions explored participants' preferences.
resultsOf the 462 respondents, 30.5% reported no problems with the composite A/D, while 13.2% reported no problems on both subdimensions. Agreement between ratings for composite and split dimensions was highest for respondents with comorbid anxiety and depression. The depression subdimension had higher correlation with PHQ-9 (r = 0.53) and GAD-7 (r = 0.33) than the composite A/D dimension (r = 0.36 and r = 0.28, respectively). The split subdimensions and composite A/D could adequately differentiate respondents based on their severity of anxiety or depression. Slightly better informativity was observed in EQ-4D-5L + anxiety (H' = 5.4; J' = 0.47) and EQ-4D-5L + depression (H' = 5.31; J' = 0.46) than EQ-5D-5L (H' = 5.19; J' = 0.45).
conclusionsAdopting two subdimensions within the EQ-5D-5L tool appears to perform slightly better than the standard EQ-5D-5L.
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