Evidence map›Paper›PMID 36809380›Full record

ArticlePloS one2023

Clinical practice guideline recommendation summaries for pediatric oncology health care professionals: A qualitative study.

Nancy Santesso, Melissa Beauchemin, Paula D Robinson, Alexandra M Walsh, Aaron J Sugalski, Tammy Lo, Ha Dang, Brian T Fisher, Allison C Grimes, Andrea Rothfus Wrightson and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Nancy SantessoDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Melissa BeaucheminColumbia University School of Nursing/Herbert Irving Cancer Center, New York, New York, United States of America.
Paula D RobinsonPediatric Oncology Group of Ontario, Toronto, Ontario, Canada.
Alexandra M WalshCenter for Cancer and Blood Disorders, Phoenix Children's Hospital, University of Arizona, Phoenix, Arizona, United States of America.
Aaron J SugalskiUniversity of Texas Health Science Center San Antonio, San Antonio, Texas, United States of America.
Tammy LoDepartment of Research and Evaluation, Kaiser Permanente, Pasadena, California, United States of America.
Ha DangBiostatistics and Data Management, Johnson and Johnson Medical Devices Companies, Irvine, California, United States of America.
Brian T FisherThe Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Allison C GrimesUniversity of Texas Health Science Center San Antonio, San Antonio, Texas, United States of America.
Andrea Rothfus WrightsonNemours Center for Cancer and Blood Disorders, Wilmington, Delaware, United States of America.
Lolie C YuLSUHSC/Children's Hospital, New Orleans, Louisiana, United States of America.
Lillian SungDivision of Haematology/Oncology, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
L Lee DupuisResearch Institute, The Hospital for Sick Children and Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-7699-1061
The University of Texas Health Science Center at San Antonio · USUniversity of Toronto · CACenter for Cancer and Blood Disorders · USChildren's Hospital of New Orleans · USChildren's Hospital of Philadelphia · USColumbia University · USImpact · CAJohnson & Johnson (United States) · USKaiser Permanente · USPediatric Oncology Group · CAUniversity of Arizona · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NCI NIH HHS UG1 CA189955
6 · The paper itself

Abstract

objectiveTo develop a summary format of clinical practice guideline (CPG) recommendations to improve understandability among health care professionals.

methodsWe developed a summary format based on current research and used the "Think Aloud" technique in one-on-one cognitive interviews to iteratively improve it. Interviews of health care professionals from Children's Oncology Group-member, National Cancer Institute Community Oncology Research Program sites were conducted. After every five interviews (a round), responses were reviewed, and changes made to the format until it was well understood and no new, substantive suggestions for revision were raised. We took a directed (deductive) approach to content analysis of the interview notes to identify concerns related to recommendation summary usability, understandability, validity, applicability and visual appeal.

resultsDuring seven rounds of interviews with 33 health care professionals, we identified important factors that influenced understandability. Participants found understanding weak recommendations more challenging than strong recommendations. Understanding was improved when the term 'conditional' recommendation was used instead of 'weak' recommendation. Participants found a Rationale section to be very helpful but desired more information when a recommendation entailed a practice change. In the final format, the recommendation strength is clearly indicated in the title, highlighted, and defined within a text box. The rationale for the recommendation is in a column on the left, with supporting evidence on the right. In a bulleted list, the Rationale section describes the benefits and harms and additional factors, such as implementation, that were considered by the CPG developers. Each bullet under the supporting evidence section indicates the level of evidence with an explanation and the supporting studies with hyperlinks when applicable.

conclusionsA summary format to present strong and conditional recommendations was created through an iterative interview process. The format is straightforward, making it easy for organizations and CPG developers to use it to communicate recommendations clearly to intended users.

Indexed as

Health PersonnelNeoplasmsChildHumansMedical OncologyQualitative Research

Identifiers

PMID36809380
PMCPMC9943009
OpenAlexW4321441726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.