Evidence map›Paper›PMID 36809356›Full record

ArticleClinical oral investigations2023

Effects of reducing excess dental adhesive on bacterial adhesion in the bracket periphery.

Christoph-Ludwig Hennig, Bijan Blochberger, Judit Symmank, Ánn Nitzsche, Sandor Nietzsche, Frank Steiniger, Marco Dederichs, André Güllmar, Markus Reise, Ulrike Schulze-Späte and 2 more

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In one paragraph

Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Christoph-Ludwig HennigDepartment of Orthodontics, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany. Christoph-Ludwig.Hennig@med.uni-jena.de.ORCID http://orcid.org/0000-0002-7776-1129
Bijan BlochbergerDepartment of Orthodontics, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Judit SymmankDepartment of Orthodontics, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Ánn NitzscheDepartment of Orthodontics, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Sandor NietzscheElectron Microscopy Center, University Hospital Jena, Ziegelmühlenweg 1, 07743, Jena, Germany.
Frank SteinigerElectron Microscopy Center, University Hospital Jena, Ziegelmühlenweg 1, 07743, Jena, Germany.
Marco DederichsDepartment of Prosthodontics, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
André GüllmarDepartment of Conservative Dentistry and Periodontology, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Markus ReiseDepartment of Conservative Dentistry and Periodontology, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Ulrike Schulze-SpäteDepartment of Conservative Dentistry and Periodontology, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Bernd SiguschDepartment of Conservative Dentistry and Periodontology, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Collin JacobsDepartment of Orthodontics, Center of Dental Medicine, University Hospital Jena, An Der Alten Post 4, 07743, Jena, Germany.
Jena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWhite spot lesions are one of the most common side effects of orthodontic therapy with a multibracket appliance and may indicate a preliminary stage of caries, also known as initial caries. Several approaches may be utilized to prevent these lesions, such as reducing bacterial adhesion in the area surrounding the bracket. This bacterial colonization can be adversely affected by a number of local characteristics. In this context, the effects of excess dental adhesive in the bracket periphery were investigated by comparing a conventional bracket system with the APC flash-free bracket system. MATERIALS AND

methodsBoth bracket systems were applied to 24 extracted human premolars, and bacterial adhesion with Streptoccocus sobrinus (S. sobrinus) was performed for 24 h, 48 h, 7 d, and 14 d. After incubation, bacterial colonization was examined in specific areas by electron microscopy.

resultsOverall, significantly fewer bacterial colonies were found in the adhesive area around the APC flash-free brackets (n = 507 ± 13 bacteria) than the conventionally bonded bracket systems (n = 850 ± 56 bacteria). This is a significant difference (**p = 0.004). However, APC flash-free brackets tend to create marginal gaps with more bacterial adhesion in this area than conventional bracket systems (n = 265 ± 31 bacteria). This bacterial accumulation in the marginal-gap area is also significant (*p = 0.029).

conclusionA smooth adhesive surface with minimal adhesive excess is beneficial for reducing bacterial adhesion but also poses a risk of marginal gap formation with subsequent bacterial colonization, which can potentially trigger carious lesions. CLINICAL RELEVANCE: To reduce bacterial adhesion, the APC flash-free bracket adhesive system with low adhesive excess might be beneficial. APC flash-free brackets reduce the bacterial colonization in the bracket environment. A lower number of bacteria can minimize white spot lesions in the bracket environment. APC flash-free brackets tend to form marginal gaps between the bracket adhesive and the tooth.

Indexed as

Dental BondingDental CariesOrthodontic BracketsBacterial AdhesionDental CementsHumansMaterials TestingDental CementsBacterial adhesionBiofilm formationBracket peripheryFlash-free bracketsWhite spot lesion

Identifiers

PMID36809356
PMCPMC10160150
OpenAlexW4321437374

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.