Evidence map›Paper›PMID 36809009›Full record

ArticleJournal of clinical microbiology2023

Fungal Integrated Histomolecular Diagnosis Using Targeted Next-Generation Sequencing on Formalin-Fixed Paraffin-Embedded Tissues.

Alexis Trecourt, Meja Rabodonirina, Claire Mauduit, Alexandra Traverse-Glehen, Mojgan Devouassoux-Shisheboran, David Meyronet, Frédérique Dijoud, Christophe Ginevra, Emmanuelle Chapey-Picq, Emilie Josse and 10 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Alexis TrecourtService de Pathologie Multi-Site-Site Sud, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Lyon, France.ORCID 0000-0002-1674-1888
Meja RabodonirinaInstitut des Agents Infectieux, Service de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Claire MauduitService de Pathologie Multi-Site-Site Sud, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Lyon, France.
Alexandra Traverse-GlehenService de Pathologie Multi-Site-Site Sud, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Lyon, France.
Mojgan Devouassoux-ShisheboranService de Pathologie Multi-Site-Site Sud, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Lyon, France.
David MeyronetFaculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon, France.
Frédérique DijoudFaculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon, France.
Christophe GinevraInstitut des Agents Infectieux, Génomique Épidémiologique des Maladies Infectieuses (GENEPII), Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Emmanuelle Chapey-PicqInstitut des Agents Infectieux, Service de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Emilie JosseInstitut des Agents Infectieux, Service de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Patricia Martins-SimoesInstitut des Agents Infectieux, Génomique Épidémiologique des Maladies Infectieuses (GENEPII), Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Abderrazzak BentaherFaculté de Médecine Lyon-Sud Charles Mérieux, UR 3738-CICLY-Equipe Inflammation et Immunité de L'épithélium Respiratoire, Université Claude Bernard Lyon 1, Lyon, France.
Damien DupontInstitut des Agents Infectieux, Service de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.ORCID 0000-0002-6992-1073
Charline MiossecInstitut des Agents Infectieux, Service de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Florence PersatFaculté de Médecine Lyon-Sud Charles Mérieux, UR 3738-CICLY-Equipe Inflammation et Immunité de L'épithélium Respiratoire, Université Claude Bernard Lyon 1, Lyon, France.
Martine WallonInstitut des Agents Infectieux, Service de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Tristan FerryFaculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon, France.
Félix PhamService de Dermatologie, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Lyon, France.
Bruno SimonInstitut des Agents Infectieux, Génomique Épidémiologique des Maladies Infectieuses (GENEPII), Hospices Civils de Lyon, Hôpital Croix-Rousse, Lyon, France.
Jean MenottiFaculté de Médecine Lyon-Sud Charles Mérieux, UR 3738-CICLY-Equipe Inflammation et Immunité de L'épithélium Respiratoire, Université Claude Bernard Lyon 1, Lyon, France.
Université Claude Bernard Lyon 1 · FRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histopathology is the gold standard for fungal infection (FI) diagnosis, but it does not provide a genus and/or species identification. The objective of the present study was to develop targeted next-generation sequencing (NGS) on formalin-fixed tissue samples (FTs) to achieve a fungal integrated histomolecular diagnosis. Nucleic acid extraction was optimized on a first group of 30 FTs with Aspergillus fumigatus or

Indexed as

MycosesFormaldehydeHigh-Throughput Nucleotide SequencingHumansParaffin EmbeddingPolymerase Chain ReactionTissue FixationFormaldehydeformalin-fixed paraffin-embedded tissuesfungal identificationhistopathologyintegrated histomolecular diagnosismassive parallel sequencingnext-generation sequencing

Identifiers

PMID36809009
PMCPMC10035294
OpenAlexW4321446560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.