Evidence map›Paper›PMID 36808826›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Fractional Dynamics Foster Deep Learning of COPD Stage Prediction.

Chenzhong Yin, Mihai Udrescu, Gaurav Gupta, Mingxi Cheng, Andrei Lihu, Lucretia Udrescu, Paul Bogdan, David M Mannino, Stefan Mihaicuta

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Fractional Dynamics Foster Deep Learning of COPD Stage Prediction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Chenzhong YinMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-6411-7441
Mihai UdrescuDepartment of Computer and Information Technology, Politehnica University of Timisoara, 2 Vasile Parvan Blvd., Timişoara, 300223, Romania.
Gaurav GuptaMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.
Mingxi ChengMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.
Andrei LihuDepartment of Computer and Information Technology, Politehnica University of Timisoara, 2 Vasile Parvan Blvd., Timişoara, 300223, Romania.
Lucretia UdrescuDepartment I - Drug Analysis, "Victor Babeş", University of Medicine and Pharmacy Timişoara, 2 Eftimie Murgu Sq., Timişoara, 300041, Romania.
Paul BogdanMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-2118-0816
David M ManninoCollege of Medicine, University of Kentucky, Lexington, KY, USA.
Stefan MihaicutaDepartment of Pulmonology, Center for Research and Innovation in Precision Medicine of Respiratory Diseases, "Victor Babes" University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., Timişoara, 300041, Romania.
University of Southern California · USPolytechnic University of Timişoara · ROVictor Babeș University of Medicine and Pharmacy Timișoara · ROUniversity of Kentucky · US

Funding

Army Research Office W911NF-17-1-0076Defense Sciences Office, DARPA N66001-17-1-4044European Union's Horizon 2020 Research and Innovation Programme 965417National Science Foundation CCF-1837131National Science Foundation CNS-1932620National Science Foundation CPS/CNS-1453860National Science Foundation MCB-1936775Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI - UEFISCDI PN-III-P2-2.1-PED-2016-1145
6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide. Current COPD diagnosis (i.e., spirometry) could be unreliable because the test depends on an adequate effort from the tester and testee. Moreover, the early diagnosis of COPD is challenging. The authors address COPD detection by constructing two novel physiological signals datasets (4432 records from 54 patients in the WestRo COPD dataset and 13824 medical records from 534 patients in the WestRo Porti COPD dataset). The authors demonstrate their complex coupled fractal dynamical characteristics and perform a fractional-order dynamics deep learning analysis to diagnose COPD. The authors found that the fractional-order dynamical modeling can extract distinguishing signatures from the physiological signals across patients with all COPD stages-from stage 0 (healthy) to stage 4 (very severe). They use the fractional signatures to develop and train a deep neural network that predicts COPD stages based on the input features (such as thorax breathing effort, respiratory rate, or oxygen saturation). The authors show that the fractional dynamic deep learning model (FDDLM) achieves a COPD prediction accuracy of 98.66% and can serve as a robust alternative to spirometry. The FDDLM also has high accuracy when validated on a dataset with different physiological signals.

Indexed as

Deep LearningPulmonary Disease, Chronic ObstructiveHumansNeural Networks, ComputerSpirometrychronic obstructive pulmonary disease (COPD)deep learningfractional analysis

Identifiers

PMID36808826
PMCPMC10131808
OpenAlexW4321349946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.