Evidence map›Paper›PMID 36808649›Full record

ArticleJournal of clinical laboratory analysis2023

Molecular characterizations of antibiotic resistance, biofilm formation, and virulence determinants of Pseudomonas aeruginosa isolated from burn wound infection.

Shirin Ghasemian, Morteza Karami-Zarandi, Hamid Heidari, Saeed Khoshnood, Ebrahim Kouhsari, Sobhan Ghafourian, Abbas Maleki, Hossein Kazemian

Open access · goldFull text read
In one paragraph

Article in Journal of clinical laboratory analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Multidrug-resistant Pseudomonas aeruginosa in ICU patients and hospital surfaces: β-lactamase burden, biofilm formation and clonal spread.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  6. Article
  7. Antibiotics (Basel, Switzerland) · 2026
    Article
  8. A Scoping Review of Fluorescence Imaging: A Promising New Technology for Bacterial Detection in Burn Wounds.Journal of burn care & research : official publication of the American Burn Association · 2026
    Article
  9. Article
  10. Viruses · 2025
    Article
  11. Article
  12. Activity of cefiderocol on extensively drug-resistantIranian journal of microbiology · 2025
    Article
  13. Viruses · 2025
    Article
  14. Article
  15. Avian Antibodies as Potential Therapeutic Tools.Antibodies (Basel, Switzerland) · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shirin GhasemianDepartment of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Morteza Karami-ZarandiDepartment of Microbiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Hamid HeidariDepartment of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.ORCID https://orcid.org/0000-0002-6869-2301
Saeed KhoshnoodClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.ORCID https://orcid.org/0000-0002-5143-3178
Ebrahim KouhsariLaboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.ORCID https://orcid.org/0000-0001-5893-6483
Sobhan GhafourianDepartment of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Abbas MalekiClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Hossein KazemianDepartment of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.ORCID https://orcid.org/0000-0003-4590-396X
Medical University of Ilam · IRGolestan University · IRShahid Sadoughi University of Medical Sciences and Health Services · IRZanjan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBurn injuries result in disruption of the skin barrier against opportunistic infections. Pseudomonas aeruginosa is one of the main infectious agents colonizing burn wounds and making severe infections. Biofilm production and other virulence factors along with antibiotic resistance limit appropriate treatment options and time. MATERIALS AND

methodsWound samples were collected from hospitalized burn patients. P. aeruginosa isolates and related virulence factors identified by the standard biochemical and molecular methods. Antibiotic resistance patterns were determined by the disc diffusion method and β-lactamase genes were detected by polymerase chain reaction (PCR) assay. To determine the genetic relatedness amongst the isolates, enterobacterial repetitive intergenic consensus (ERIC)-PCR was also performed.

resultsForty P. aeruginosa isolates were identified. All of these isolates were biofilm producers. Carbapenem resistance was detected in 40% of the isolates, and bla

conclusionAntibiotic resistance, particularly carbapenem resistance was considerable among the P. aeruginosa isolates colonizing burn wounds. Combining carbapenem resistance with biofilm production and virulence factors would result in severe and difficult-to-treat infections.

Indexed as

BurnsPseudomonas InfectionsWound InfectionAnti-Bacterial Agentsbeta-LactamasesBiofilmsCarbapenemsDrug Resistance, MicrobialHumansMicrobial Sensitivity TestsPseudomonas aeruginosaVirulenceVirulence FactorsAnti-Bacterial Agentsbeta-LactamasesCarbapenemsVirulence Factorsbiofilmburn injuriescarbapenem-resistantERIC-PCRPseudomonas aeruginosa

Identifiers

PMID36808649
PMCPMC10020843
OpenAlexW4321333599

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read109
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.