ArticleInternal and emergency medicine2023
Effects of continuous positive airway pressure on comprehensive geriatric assessment and cognitive function in elderly patients with obstructive sleep apnea syndrome.
Article in Internal and emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 16 citations in OpenAlex.
- Impact of CPAP therapy on geriatric depression scale scores in elderly patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2026Article
- Assessment of sleep in older people within comprehensive geriatric assessments: a scoping review.Age and ageing · 2026Article
- Effect of CPAP treatment on subjective cognitive decline in patients with mild obstructive sleep apnea syndrome.Sleep and biological rhythms · 2026Article
- [Analysis of the incidence and influencing factors of collateral circulation in high-risk patients with sleep apnea complicated with stroke treated by continuous positive pressure ventilation].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Article
- Sleep disorders after cardiac arrest: Prevalence and relation with cognitive function.Resuscitation plus · 2025Article
- Differences in the clinical presentation of sleep apnea patients according to age and gender.PloS one · 2025Article
- Correlation of telomere length and DNA damage markers with severity and associated depressive states in patients with OSAS.Frontiers in neurology · 2025Article
- Effects of Continuous Positive Airway Pressure Treatment on Vascular Function in a Real-Life Cohort of Elderly Patients with Obstructive Sleep Apnoea Syndrome.Biomedicines · 2024Article
- Non-dipper blood pressure pattern and glycemic alterations: does post-prandial glucose rise predict lack of nocturnal pressure drop?Internal and emergency medicine · 2024Article
- Effects of continuous positive airway pressure on comprehensive geriatric assessment and cognitive function in elderly patients with obstructive sleep apnea syndrome: comment.Internal and emergency medicine · 2024Article
- Exploring additional strategy to improving cognitive skills in older adults.Internal and emergency medicine · 2023Article
- Association of sleep behaviors, insulin resistance surrogates, and the risk of hypertension in Chinese adults with type 2 diabetes mellitus.Frontiers in endocrinology · 2023Article
- Investigating associations between social determinants, self-efficacy measurement of sleep apnea and CPAP adherence: the SEMSA study.Frontiers in neurology · 2023Article
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14 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea syndrome (OSAS) can lead to cognitive impairment and depression affecting memory, attention, and executive functions. Continuous positive airway pressure (CPAP) treatment seems to be able to revert changes in brain networks and neuropsychological tests correlated to OSAS. The aim of the present study was to evaluate the effects of a 6-month treatment with CPAP on functional, humoral and cognitive parameters in a cohort of elderly OSAS patients with several comorbidities. We enrolled 360 elderly patients suffering from moderate to severe OSAS and indication for nocturnal CPAP. At baseline the Comprehensive Geriatric Assessment (CGA) revealed a borderline Mini-Mental State Examination (MMSE) score that improved after 6-month treatment with CPAP (25.3 ± 1.6 vs 26 ± 1.5; p < 0.0001), as well as the Montreal Cognitive Assessment (MoCA) showed a mild improvement (24.4 ± 2.3 vs 26.2 ± 1.7; p < 0.0001). Moreover, functionality activities increased after treatment, as documented by a short physical performance battery (SPPB) (6.3 ± 1.5 vs 6.9 ± 1.4; p < 0.0001). Reduction of the Geriatric Depression Scale (GDS) from 6.0 ± 2.5 to 4.6 ± 2.2 (p < 0.0001) was also detected. Changes of homeostasis model assessment (HOMA) index, oxygen desaturation index (ODI), sleep-time spent with saturation below 90% (TC90), peripheral arterial oxyhaemoglobin saturation (SpO
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