Evidence map›Paper›PMID 36808577›Full record

ArticleClinical and experimental medicine2023

T lymphocyte subsets and immunoglobulin and complement levels are associated with the infection status of patients with antineutrophil cytoplasmic antibody-associated vasculitis.

Rui Liu, Mengdi Li, Lei Zhang, Yan Wang, Wei Li, Shengyun Liu

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Article in Clinical and experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Rui LiuDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengdi LiDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lei ZhangDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yan WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wei LiDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. libuwei2011@163.com.ORCID http://orcid.org/0000-0002-4073-4397
Shengyun LiuDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. fccliusy2@zzu.edu.cn.ORCID http://orcid.org/0000-0002-0426-1705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfection is the leading cause of death in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). The aim of this study was to characterize the immunological features of infectious events occurring in patients with newly diagnosed AAV and to identify possible risk factors associated with infection.

methodsThe T lymphocyte subsets, immunoglobulin, and complement levels of the groups were compared between infected group and the noninfected group. Further, regression analysis was conducted to determine the association of each variable with the risk of infection.

results280 patients with newly diagnosed AAV were enrolled. The average levels of CD3

conclusionsPatients of infected AAV and those without infection differ in T lymphocyte subsets and immunoglobulin and complement levels. Furthermore, CD3

Indexed as

Antibodies, Antineutrophil CytoplasmicAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisCD8-Positive T-LymphocytesHumansImmunoglobulin GT-Lymphocyte SubsetsAntibodies, Antineutrophil CytoplasmicImmunoglobulin GANCA-associated vasculitisComplementImmunoglobulinInfectionT lymphocyte subset

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.