Evidence map›Paper›PMID 36808396›Full record

ArticleInternational urology and nephrology2023

Low-density lipoprotein cholesterol to apolipoprotein B ratio predicts mortality and cardiovascular events in peritoneal dialysis patients.

Chuanfei Zeng, Qing Zhan, Linghai Lv, Yanbing Chen, Xiaojiang Zhan

Abstract read
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In one paragraph

Article in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chuanfei ZengDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, 17#Yongwai Street, Nanchang, 330006, Jiangxi, China.
Qing ZhanDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, 17#Yongwai Street, Nanchang, 330006, Jiangxi, China.
Linghai LvDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, 17#Yongwai Street, Nanchang, 330006, Jiangxi, China.
Yanbing ChenDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, 17#Yongwai Street, Nanchang, 330006, Jiangxi, China.
Xiaojiang ZhanDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, 17#Yongwai Street, Nanchang, 330006, Jiangxi, China. zhanxiaogang87@163.com.ORCID http://orcid.org/0000-0003-2371-1350
Nanchang University · CNShangrao Normal University · CN

Funding

Natural Science Foundation of Jiangxi Province 20212BAB216020Project of Administration of Traditional Chinese Medicine of Jiangxi Province of China 2020Z020the Science and Technology Program of Jiangxi Health Commission 20195075
6 · The paper itself

Abstract

purposeThe ratio of low-density lipoprotein cholesterol (LDL-C)/apolipoprotein B (apo B) is associated with all-cause mortality and cardiovascular events in chronic kidney disease patients. The aim of this study was to investigate the association between the LDL-C/apo B ratio (LAR) and all-cause mortality and cardiovascular events in peritoneal dialysis (PD) patients.

methodsA total of 1199 incident PD patients were enrolled from November 1, 2005 to August 31, 2019. The LAR was used to divide the patients into two groups by X-Tile software and restricted cubic splines using 1.04 as the cutoff. The incidence of all-cause mortality and cardiovascular events at follow-up was compared according to LAR.

resultsOf the 1199 patients, 58.0% were men, the mean age was 49.3 ± 14.5 years, 225 patients had a history of diabetes, and 117 patients had prior cardiovascular disease. During the follow-up period, 326 patients died, and 178 patients experienced cardiovascular events. After full adjustment, a low LAR was significantly associated with HRs for all-cause mortality of 1.37 (95% CI 1.02-1.84, P = 0.034) and for cardiovascular events of 1.61 (95% CI 1.10-2.36, P = 0.014).

conclusionThis study suggests that a low LAR is an independent risk factor for all-cause mortality and cardiovascular events in PD patients, indicating that the LAR may provide significant information when assessing all-cause mortality and cardiovascular risks.

Indexed as

Cardiovascular DiseasesPeritoneal DialysisAdultApolipoproteins BCholesterol, LDLFemaleHumansMaleMiddle AgedRisk FactorsApolipoproteins BCholesterol, LDLAll-cause mortalityApolipoprotein BCardiovascular eventsLow-density lipoprotein cholesterolPeritoneal dialysis

Identifiers

PMID36808396
OpenAlexW4321325880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.