Evidence map›Paper›PMID 36808257›Full record

ArticleJournal of mammary gland biology and neoplasia2023

Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential.

Alex Cordero, Patricia G Santamaría, Eva González-Suárez

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of mammary gland biology and neoplasia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. RANK/RANKL Signaling Pathway in Breast Development and Cancer.Advances in experimental medicine and biology · 2025
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Alex Cordero *Oncobell, Bellvitge Biomedical Research Institute, IDIBELL, 08908, Barcelona, Spain.
Patricia G Santamaría *Molecular Oncology, Spanish National Cancer Research Centre (CNIO), 28029, Madrid, Spain.
Eva González-SuárezOncobell, Bellvitge Biomedical Research Institute, IDIBELL, 08908, Barcelona, Spain. egonzalez@cnio.es.
Institut d'Investigació Biomédica de Bellvitge · ESNeurological Surgery · USSpanish National Cancer Research Centre · ES

Funding

European Research Council 682935
6 · The paper itself

Abstract

Determination of the mammary epithelial cell that serves as the cell of origin for breast cancer is key to understand tumor heterogeneity and clinical management. In this study, we aimed to decipher whether Rank expression in the presence of PyMT and Neu oncogenes might affect the cell of origin of mammary gland tumors. We observed that Rank expression in PyMT

Indexed as

Ectopic Gene ExpressionMammary Neoplasms, ExperimentalAnimalsCarcinogenesisEpithelial CellsHumansMiceMice, TransgenicOncogenesCancer stem cellCell of originMammary epithelial cellMetastasisNeuPyMTRankTumor initiating cell

Identifiers

PMID36808257
PMCPMC9938814
OpenAlexW4321352501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.