Evidence map›Paper›PMID 36808225›Full record

ArticleArchives of dermatological research2023

The stereological, immunohistological, and gene expression studies in an infected ischemic wound in diabetic rats treated by human adipose-derived stem cells and photobiomodulation.

Roohollah Ebrahimpour-Malekshah, Abdollah Amini, Atarodalsadat Mostafavinia, Houssein Ahmadi, Fatemeh Zare, Sobhan Safaju, Amirhossein Shahbazi, Sufan Chien, Fatemehalsadat Rezaei, Anwarul Hasan and 1 more

Abstract read
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In one paragraph

Article in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  12. Photobiomodulation studies on diabetic wound healing: An insight into the inflammatory pathway in diabetic wound healing.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Roohollah Ebrahimpour-MalekshahMazandaran University of Medical Sciences, Sari, Iran.
Abdollah AminiDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Atarodalsadat MostafaviniaDepartment of Anatomy, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Houssein AhmadiDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh ZareDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sobhan SafajuDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Amirhossein ShahbaziDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sufan ChienPrice Institute of Surgical Research, University of Louisville, Noveratech LLC of Louisville, Louisville, KY, USA.
Fatemehalsadat RezaeiCollege of Pharmacy, University of Kentucky, 789 South Limestone, Lexington, KY, 40536, USA.ORCID http://orcid.org/0000-0001-5699-9907
Anwarul HasanDepartment of Mechanical and Industrial Engineering, College of Engineering, Qatar University, 2713, Doha, Qatar. ahasan@qu.edu.qa.ORCID http://orcid.org/0000-0001-8380-2233
Mohammad BayatPrice Institute of Surgical Research, University of Louisville, Noveratech LLC of Louisville, Louisville, KY, USA. bayat_m@yahoo.com.ORCID http://orcid.org/0000-0001-5214-4223
Shahid Beheshti University of Medical Sciences · IRUniversity of Louisville · USIslamic Azad University Medical Branch of Tehran · IRMazandaran University of Medical Sciences · IRQatar University · QAUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the impacts of photobiomodulation (PBM) and human allogeneic adipose-derived stem cells (ha-ADS) together and or alone applications on the stereological parameters, immunohistochemical characterizing of M1 and M2 macrophages, and mRNA levels of hypoxia-inducible factor (HIF-1α), basic fibroblast growth factor (bFGF), vascular endothelial growth factor-A (VEGF-A) and stromal cell-derived factor-1α (SDF-1α) on inflammation (day 4) and proliferation phases (day 8) of repairing tissues in an infected delayed healing and ischemic wound model (IDHIWM) in type 1 diabetic (DM1) rats. DM1 was created in 48 rats and an IDHIWM was made in all of them, and they were distributed into 4 groups. Group1 = control rats with no treatment. Group2 = rats received (10 × 100000 ha-ADS). Group3 = rats exposed to PBM (890 nm, 80 Hz, 3.46 J/cm

Indexed as

Diabetes Mellitus, ExperimentalLow-Level Light TherapyAnimalsChemokine CXCL12Gene ExpressionHumansInflammationRatsStem CellsVascular Endothelial Growth Factor AChemokine CXCL12Vascular Endothelial Growth Factor AAdipose-derived stem cellsDiabetes mellitusGene expressionImmunohistochemical studyLow-level laser therapyMacrophagesPhotobiomodulationRatStereological examinationWound healing

Identifiers

PMID36808225
OpenAlexW4321435993

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.