Evidence map›Paper›PMID 36808215›Full record

ReviewIntensive care medicine2023

How to manage coagulopathies in critically ill patients.

Julie Helms, Toshiaki Iba, Jean Marie Connors, Satoshi Gando, Marcel Levi, Ferhat Meziani, Jerrold H Levy

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Intensive care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 84 citations in OpenAlex.

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  16. Beyond the count: platelet dysfunction profile in pediatric trauma patients.Research and practice in thrombosis and haemostasis · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Julie HelmsUniversité de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, Service de Médecine Intensive-Réanimation, Nouvel Hôpital Civil, 1, place de l'Hôpital, 67091, Strasbourg Cedex, France. Julie.helms@chru-strasbourg.fr.ORCID http://orcid.org/0000-0003-0895-6800
Toshiaki IbaDepartment of Emergency and Disaster Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Jean Marie ConnorsHematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Satoshi GandoDepartment of Acute and Critical Care Medicine, Sapporo Higashi Tokushukai Hospital, Sapporo, USA.
Marcel LeviDepartment of Vascular Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Ferhat MezianiUniversité de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, Service de Médecine Intensive-Réanimation, Nouvel Hôpital Civil, 1, place de l'Hôpital, 67091, Strasbourg Cedex, France.
Jerrold H LevyDepartment of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, NC, USA.
Inserm · FRBrigham and Women's Hospital · USDuke University · USHokkaido University · JPJuntendo University · JPUCL Biomedical Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coagulopathy is a severe and frequent complication in critically ill patients, for which the pathogenesis and presentation may be variable depending on the underlying disease. Based on the dominant clinical phenotype, the current review differentiates between hemorrhagic coagulopathies, characterized by a hypocoagulable and hyperfibrinolysis state, and thrombotic coagulopathies with a systemic prothrombotic and antifibrinolytic phenotype. We discuss the differences in pathogenesis and treatment of the common coagulopathies.

Indexed as

Blood Coagulation DisordersDisseminated Intravascular CoagulationThrombosisCritical IllnessHumansPhenotypeCoagulopathyCritical careDisseminated intravascular coagulationHematological diseaseSepsisTrauma

Identifiers

PMID36808215
OpenAlexW4321185909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.