Evidence map›Paper›PMID 36808007›Full record

ReviewActa neurochirurgica2023

Malignant transformation of adult-onset pilocytic astrocytoma to diffuse leptomeningeal glioneuronal tumor within the thoracic spine: a case report and review of the literature.

Pedram Laghaei Farimani, Alexander D Rebchuk, Stephano J Chang, Stephen Yip, Cynthia Hawkins, Tamir T Ailon

Abstract readReviewCase Reports
PubMed Publisher
In one paragraph

Review in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pedram Laghaei FarimaniMD Undergraduate Program, Faculty of Medicine, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada. pedramlf@student.ubc.ca.ORCID http://orcid.org/0000-0001-8883-1586
Alexander D RebchukDivision of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
Stephano J ChangDivision of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
Stephen YipDivision of Neuropathology, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
Cynthia HawkinsDivision of Neuropathology, Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, ON, Canada.
Tamir T AilonDivision of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
University of British Columbia · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a 31-year-old male who presented with progressive myelopathy from a thoracic pilocytic astrocytoma (PA). Following multiple recurrences and resections, 10 years after his index surgery, pathology revealed diffuse leptomeningeal glioneuronal tumor (DLGNT) with high-grade features. We discuss his clinical course, management, histopathological findings, and present a comprehensive review of spinal PA undergoing malignant transformation in adults and adult-onset spinal DLGNT. To our knowledge, we present the first reported case of adult-onset spinal PA malignant transformation to DLGNT. Our case adds to the paucity of clinical data characterizing such transformations and highlights the importance of developing novel management paradigms.

Indexed as

AstrocytomaCentral Nervous System NeoplasmsMeningeal NeoplasmsSpinal Cord NeoplasmsAdultHumansMaleSpineCase reportDiffuse leptomeningeal glioneuronal tumorDLGNTMalignant transformationPilocytic astrocytomaSpinal tumor

Identifiers

PMID36808007
OpenAlexW4321349474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.