Evidence map›Paper›PMID 36808000›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

A cycle-consistent adversarial network for brain PET partial volume correction without prior anatomical information.

Amirhossein Sanaat, Hossein Shooli, Andrew Stephen Böhringer, Maryam Sadeghi, Isaac Shiri, Yazdan Salimi, Nathalie Ginovart, Valentina Garibotto, Hossein Arabi, Habib Zaidi

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Comparison of the Correlation Between Cerebral [Molecular imaging and biology · 2025
    Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amirhossein SanaatDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Hossein ShooliPersian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy (MIRT), Bushehr Medical University Hospital, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
Andrew Stephen BöhringerDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Maryam SadeghiDepartment of Medical Statistics, Informatics and Health Economics, Medical University of Innsbruck, Schoepfstr. 41, Innsbruck, Austria.
Isaac ShiriDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Yazdan SalimiDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Nathalie GinovartGeneva University Neurocenter, University of Geneva, Geneva, Switzerland.
Valentina GaribottoDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Hossein ArabiDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Habib ZaidiDivision of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland. habib.zaidi@hcuge.ch.ORCID 0000-0001-7559-5297

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung SNSF 320030_176052
6 · The paper itself

Abstract

purposePartial volume effect (PVE) is a consequence of the limited spatial resolution of PET scanners. PVE can cause the intensity values of a particular voxel to be underestimated or overestimated due to the effect of surrounding tracer uptake. We propose a novel partial volume correction (PVC) technique to overcome the adverse effects of PVE on PET images.

methodsTwo hundred and twelve clinical brain PET scans, including 50

resultsThe Bland and Altman analysis showed the largest and smallest variance for

conclusionAn end-to-end CycleGAN PVC method was developed and evaluated. Our model generates PVC images from the original non-PVC PET images without requiring additional anatomical information, such as MRI or CT. Our model eliminates the need for accurate registration or segmentation or PET scanner system response characterization. In addition, no assumptions regarding anatomical structure size, homogeneity, boundary, or background level are required.

Indexed as

Aniline CompoundsFluorodeoxyglucose F18BenzothiazolesBrainDihydroxyphenylalanineHumansImage Processing, Computer-AssistedPositron-Emission TomographyAniline CompoundsBenzothiazolesDihydroxyphenylalanineFluorodeoxyglucose F18fluorodopa F 18flutemetamolBrainDeep learningPartial volume correctionPartial volume effectPET

Identifiers

PMID36808000
PMCPMC10199868

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.