SynthesisJournal of endocrinological investigation2023
The relationship between air pollutants and gestational diabetes: an updated systematic review and meta-analysis.
Synthesis in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- The China Birth Cohort-Environmental and Genetic Factors (CBC-EG) Study: Design, Aims, Protocol, Findings, and Prospects.Environment & health (Washington, D.C.) · 2026Review
- Article
- Longitudinal associations between PMFrontiers in cellular and infection microbiology · 2026Article
- Hyperglycaemia in pregnancy: the role of ethnicity and geography in risk and outcomes.Diabetologia · 2025Review
- Long-Term Exposure to Ambient Air Pollution and Metabolic Syndrome and Its Components.Journal of obesity & metabolic syndrome · 2025Review
- Mediating effect of diabetes in the association between long-term PMScientific reports · 2025Article
- Article
- Impact of climate change and environmental adversities on maternal and fetal health: the role of clinical practices and providers in mitigating effects and prioritising women's health in the UK.Frontiers in global women's health · 2025Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAir pollution is an environmental stimulus that may predispose pregnant women to gestational diabetes mellitus (GDM). This systematic review and meta-analysis were conducted to investigate the relationship between air pollutants and GDM.
methodsPubMed, Web of Science, and Scopus were systematically searched for retrieving English articles published from January 2020 to September 2021, investigating the relationship of exposure to ambient air pollution or levels of air pollutants with GDM and related parameters, including fasting plasma glucose (FPG), insulin resistance, and impaired glucose tolerance. Heterogeneity and publication bias were evaluated using I-squared (I2), and Begg's statistics, respectively. We also performed the subgroup analysis for particulate matters (PM2.5, PM10), Ozone (O3), and sulfur dioxide (SO2) in the different exposure periods.
resultsA total of 13 studies examining 2,826,544 patients were included in this meta-analysis. Compared to non-exposed women, exposure to PM2.5 increases the odds (likelihood of occurrence outcome) of GDM by 1.09 times (95% CI 1.06, 1.12), whereas exposure to PM10 has more effect by OR of 1.17 (95% CI 1.04, 1.32). Exposure to O3 and SO2 increases the odds of GDM by 1.10 times (95% CI 1.03, 1.18) and 1.10 times (95% CI 1.01, 1.19), respectively.
conclusionsThe results of the study show a relationship between air pollutants PM2.5, PM10, O3, and SO2 and the risk of GDM. Although evidence from various studies can provide insights into the linkage between maternal exposure to air pollution and GDM, more well-designed longitudinal studies are recommended for precise interpretation of the association between GDM and air pollution by adjusting all potential confounders.
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