Evidence map›Paper›PMID 36807740›Full record

ArticleNutrition bulletin2023

Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health improvement strategies.

A Caffrey, Y Lamers, M M Murphy, N Letourneau, R E Irwin, K Pentieva, M Ward, A Tan, A Rojas-Gómez, L A Santos-Calderón and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Nutrition bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 3 countries.

A CaffreyNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, Coleraine, UK.ORCID 0000-0002-7991-7262
Y LamersBritish Columbia Children's Hospital Research Institute, Food Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, British Columbia, Canada.
M M MurphyUnit of Preventive Medicine & Public Health, Department of Basic Medical Sciences, Faculty of Medicine & Health Sciences, Universitat Rovira i Virgili, IISPV, Reus, Spain.
N LetourneauFaculty of Nursing and Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
R E IrwinGenomic Medicine Group, School of Biomedical Sciences, Ulster University, Coleraine, UK.
K PentievaNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, Coleraine, UK.
M WardNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, Coleraine, UK.
A TanBritish Columbia Children's Hospital Research Institute, Food Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, British Columbia, Canada.
A Rojas-GómezUnit of Preventive Medicine & Public Health, Department of Basic Medical Sciences, Faculty of Medicine & Health Sciences, Universitat Rovira i Virgili, IISPV, Reus, Spain.
L A Santos-CalderónUnit of Preventive Medicine & Public Health, Department of Basic Medical Sciences, Faculty of Medicine & Health Sciences, Universitat Rovira i Virgili, IISPV, Reus, Spain.
J Canals-SansDepartment of Psychology, Faculty of Educational Sciences and Psychology, Universitat Rovira i Virgili, Tarragona, Spain.
B M Y LeungFaulty of Health Sciences, University of Lethbridge, Lethbridge, Alberta, Canada.
R BellFaculty of Agricultural, Life and Environment Science, University of Alberta, Edmonton, Alberta, Canada.
G F GiesbrechtFaculty of Nursing and Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
D DeweyFaculty of Nursing and Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
C J FieldFaculty of Agricultural, Life and Environment Science, University of Alberta, Edmonton, Alberta, Canada.
M KoborBritish Columbia Children's Hospital Research Institute, Food Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, British Columbia, Canada.
C P WalshGenomic Medicine Group, School of Biomedical Sciences, Ulster University, Coleraine, UK.
H McNultyNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, Coleraine, UK.
University of Ulster · GBUniversity of British Columbia · CAUniversity of Calgary · CAInstitut de Recerca Biomèdica Catalunya Sud · ESUniversity of Alberta · CAInstituto de Salud Carlos III · ESUniversitat Rovira i Virgili · ESUniversity of Lethbridge · CA

Funding

Biotechnology and Biological Sciences Research Council BB/S020330/1
6 · The paper itself

Abstract

Suboptimal status of folate and/or interrelated B vitamins (B

Indexed as

Folic AcidVitamin B ComplexAgedBrainChildDietEpigenesis, GeneticFemaleHumansPregnancyVitamin AVitamin KFolic AcidVitamin AVitamin B ComplexVitamin KageingB vitaminscognitionDNA methylationfolateone-carbon metabolism

Identifiers

PMID36807740
PMCPMC10946506
OpenAlexW4321446082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.