Evidence map›Paper›PMID 36807489›Full record

ArticleScandinavian journal of work, environment & health2023

Association of occupational heat exposure and colorectal cancer in the MCC-Spain study.

Alice Hinchliffe, Manolis Kogevinas, Antonio J Molina, Victor Moreno, Nuria Aragonés, Gemma Castaño-Vinyals, José Juan Jiménez Moleón, Inés Gómez Acebo, María Ederra, Pilar Amiano and 8 more

Open access · goldAbstract read
In one paragraph

Article in Scandinavian journal of work, environment & health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Five decades of occupational cancer epidemiology.Scandinavian journal of work, environment & health · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 1 country.

Alice Hinchliffe
Manolis Kogevinas
Antonio J Molina
Victor Moreno
Nuria Aragonés
Gemma Castaño-Vinyals
José Juan Jiménez Moleón
Inés Gómez Acebo
María Ederra
Pilar Amiano
Ana Molina-Barceló
Guillermo Fernandez-Tardon
Juan Alguacil
María-Dolores Chirlaque
Natalia Hernández-Segura
Beatriz Pérez-Gómez
Marina Pollan
Michelle C TurnerISGlobal, Barcelona Institute for Global Health, Parc de Recerca Biomèdica de Barcelona, Doctor Aiguader, 88 Barcelona 08003 Spain. michelle.turner@isglobal.org.
Navarre Institute of Health Research · ESBarcelona Institute for Global Health · ESBasque Government · ESFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESHospital del Mar Research Institute · ESInstitut Català d'Oncologia · ESInstituto de Investigación Marqués de Valdecilla · ESInstituto de Salud Pública de Navarra · ESInstituto Murciano de Investigación Biosanitaria · ESMunicipal Institute for Medical Research · ESPompeu Fabra University · ESUniversidad de León · ESUniversidad de Oviedo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHeat exposure and heat stress/strain is a concern for many workers. There is increasing interest in potential chronic health effects of occupational heat exposure, including cancer risk. We examined potential associations of occupational heat exposure and colorectal cancer (CRC) risk in a large Spanish multi-case--control study.

methodsWe analyzed data on 1198 histologically confirmed CRC cases and 2690 frequency-matched controls. The Spanish job-exposure matrix, MatEmEsp, was used to assign heat exposure estimates to the lifetime occupations of participants. Three exposure indices were assessed: ever versus never exposed, cumulative exposure and duration (years). We estimated odds ratios (OR) and 95% confidence intervals (CI) using unconditional logistic regression adjusting for potential confounders.

resultsOverall, there was no association of ever, compared with never, occupational heat exposure and CRC (OR 1.09, 95% CI 0.92-1.29). There were also no associations observed according to categories of cumulative exposure or duration, and there was no evidence for a trend. There was no clear association of ever occupational heat exposure and CRC in analysis conducted among either men or women when analyzed separately. Positive associations were observed among women in the highest categories of cumulative exposure (OR 1.81, 95% CI 1.09-3.03) and duration (OR 2.89, 95% CI 1.50-5.59) as well as some evidence for a trend (P<0.05).

conclusionOverall, this study provides no clear evidence for an association between occupational heat exposure and CRC.

Indexed as

Colorectal NeoplasmsOccupational DiseasesOccupational ExposureCase-Control StudiesFemaleHumansLogistic ModelsMaleRisk FactorsSpain

Identifiers

PMID36807489
PMCPMC10621896
OpenAlexW4321349378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.