Evidence map›Paper›PMID 36807105›Full record

Trial reportSpine deformity2023

A United States multi-site randomized control trial of Schroth-based therapy in adolescents with mild idiopathic scoliosis.

Karina Amani Zapata, Rebecca J Dieckmann, M Timothy Hresko, Paul D Sponseller, Michael G Vitale, Steven D Glassman, Brian G Smith, Chan-Hee Jo, Daniel J Sucato

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Spine deformity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 5 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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  6. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Karina Amani ZapataScottish Rite for Children, 2222 Welborn Street, Dallas, TX, 75219, USA. Karina.zapata@tsrh.org.ORCID http://orcid.org/0000-0002-0187-5648
Rebecca J DieckmannScottish Rite for Children, 2222 Welborn Street, Dallas, TX, 75219, USA.
M Timothy HreskoBoston Children's Hospital, Boston, MA, USA.
Paul D SponsellerJohns Hopkins University, Baltimore, MD, USA.
Michael G VitaleColumbia University Medical Center, New York, NY, USA.
Steven D GlassmanNorton Leatherman Spine Center, Louisville, KY, USA.
Brian G SmithTexas Children's, Houston, TX, USA.
Chan-Hee JoScottish Rite for Children, 2222 Welborn Street, Dallas, TX, 75219, USA.
Daniel J SucatoScottish Rite for Children, 2222 Welborn Street, Dallas, TX, 75219, USA.
Texas Scottish Rite Hospital for Children · USBoston Children's Hospital · USColumbia University Irving Medical Center · USJohns Hopkins University · USNorton Healthcare · USTexas Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to determine the feasibility and efficacy of a United States multi-site randomized control trial (RCT) of the Schroth-based therapy program in Risser 0 patients with mild adolescent idiopathic scoliosis (AIS) curves.

methodsSix sites enrolled 98 Risser 0 patients with single AIS curves between 12° and 24°. Patients were randomized to Exercise:Control group in a 2:1 ratio. Exercise group patients were instructed on the Schroth-based method and a home exercise program of 75 min/week for 1 year.

resultsEnrollment across 6 institutions averaged 2.2 patients per month over 45 months. Patient attrition was 42% after 1 year (41/98) and 52% after 2 years (51/98). Exercise group patients were significantly younger (11.6 vs 12.5 years) without differences in the baseline Cobb angle (16.2° vs 17.1°). Self-reported exercise adherence averaged 82% at 6 months and 63% at 1 year (n = 35). A significantly lower frequency of patients was braced in the Exercise group after 1 year (26% vs 55%, p = 0.03) but not after 2 years (48% vs 63%, p = 0.31). Curve magnitude changes between groups were not significant after 1 and 2 years.

conclusionPerforming a multi-site RCT for mild AIS in the United States is challenging with slow enrollment and high attrition. Young patients with small curves have difficulty adhering to the intensive demands of Schroth-based therapy. LEVEL OF EVIDENCE: II.

Indexed as

KyphosisScoliosisAdolescentBracesExercise TherapyHumansTreatment OutcomeEX trialScoliosis-specific exerciseSpine deformity

Identifiers

PMID36807105
OpenAlexW4321349666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.