ArticleJournal, genetic engineering & biotechnology2023
Characterization, antimicrobial and antitumor activity of superoxide dismutase extracted from Egyptian honeybee venom (Apis mellifera lamarckii).
Article in Journal, genetic engineering & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Bioactive metabolites from marine fungal sources: evaluation of antimicrobial and cytotoxic activities.BMC microbiology · 2026Article
- Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025Article
- Assessing the Influence of Stimulatory Feeding of Bee Colonies on Mineral Composition and Antioxidant Activity of Bee Venom.Insects · 2025Article
- Antimicrobial proteins from oyster hemolymph improve the efficacy of conventional antibiotics.PloS one · 2025Article
- The Anti-Leukemic Potential of Bee Venom.International journal of general medicine · 2025Review
- Structural, dielectric, and antimicrobial evaluation of PMMA/CeOScientific reports · 2024Article
- Chemical Composition and Antimicrobial Properties of Honey Bee Venom.Molecules (Basel, Switzerland) · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
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Abstract
backgroundSuperoxide dismutase is an important antioxidative stress enzyme which is found in honeybee venom and has a wide pharmaceutical and medical applications.
resultsWe reported the purification and characterization of venom SOD from Egyptian honeybee Apis mellifera lamarckii and termed BVSOD. It was purified to homogeneity from the Egyptian honeybee venom. The purification procedures included crude extraction, DEAE-cellulose anion exchange column chromatography, and Sephacryl S-300 gel filtration column chromatography. The purified BVSOD is found to be homogeneous as investigated by native PAGE. It exhibited homodimeric structure with a molecular weight of native form of 32 kDa and subunits of 16.0 kDa. It displayed the maximum activity at pH 7.4. CuCl
conclusionsThe purified BVSOD is found to have antimicrobial and antitumor activities which can be used for various medical and clinical applications.
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