ArticleBreast cancer research and treatment2023
Single-institution outcomes after excision of benign phyllodes tumors: low recurrence risk even with positive margins.
Article in Breast cancer research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Phyllodes tumors of the breast: a comprehensive review.Annals of surgical treatment and research · 2026Review
- Phyllodes tumors of the breast: Real world data from a multi-institution cohort.Breast (Edinburgh, Scotland) · 2025Article
- Local recurrence of phyllodes tumors after surgery with wide compared to narrow margins: study protocol for a systematic review and meta-analysis.Systematic reviews · 2025Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeBenign phyllodes tumors (BPT) are rare breast neoplasms with clinical behavior that poses low recurrence risk. Guidelines regarding appropriate margins recommend surgical excision to negative margins, sometimes requiring re-excision surgery. Contemporary experience suggests that re-excision in the face of positive margins may not be needed.
methodsThis is a retrospective review of a single-institution experience with BPT from 2010 to 2019 with 102 patients. Demographics, outcomes and follow-up were analyzed.
resultsThe median age was 37 years. 95% had a pre-operative biopsy and only 6% were confirmed BPT before surgery.56% had positive margins and were more likely to be younger and have a pre-operative diagnosis of fibroadenoma. The median follow-up was 33 months. Between the positive and negative margin groups, recurrence rates were not significantly different (p = 0.87).
conclusionPositive margins on excision of BPT poses a low recurrence risk and re-excision surgery is not necessary.
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Registered trials
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