Evidence map›Paper›PMID 36806992›Full record

ArticleJournal of neurology2023

The association of subjective sleep characteristics and plasma biomarkers of Alzheimer's disease pathology in older cognitively unimpaired adults with higher amyloid-β burden.

Heling Chu, Chuyi Huang, Ya Miao, Chenxi Ren, Yihui Guan, Fang Xie, Zhuo Fang, Qihao Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Non-linear associations between sleep duration and plasma p-tau181 in the Framingham Heart Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Article
  6. Article
  7. Lifestyle factors and plasma biomarkers of Alzheimer's disease: A narrative review.The journal of prevention of Alzheimer's disease · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Menopausal vasomotor symptoms and plasma Alzheimer disease biomarkers.American journal of obstetrics and gynecology · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Heling ChuDepartment of Gerontology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600, Yi Shan Road, Shanghai, China.
Chuyi HuangHealth Management Center, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ya MiaoDepartment of Gerontology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600, Yi Shan Road, Shanghai, China.
Chenxi RenDepartment of Gerontology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600, Yi Shan Road, Shanghai, China.
Yihui GuanPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Fang XiePET Center, Huashan Hospital, Fudan University, Shanghai, China.
Zhuo FangDepartment of Data and Analytics, WuXi Diagnostics, Shanghai, China. fang_zhuo@wuxidiagnostics.com.
Qihao GuoDepartment of Gerontology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 600, Yi Shan Road, Shanghai, China. qhguo@sjtu.edu.cn.
Shanghai Sixth People's Hospital · CNFudan University · CNShanghai Jiao Tong University · CNWuXi AppTec (China) · CN

Funding

Guangdong Provincial Key S&T Program 2018B030336001National Natural Science Foundation of China 81901102National Natural Science Foundation of China 82071472National Natural Science Foundation of China 82171198Shanghai Municipal Science and Technology Major Project 2018SHZDZX01Shanghai Pujiang Program 21PJ1423100
6 · The paper itself

Abstract

We aimed to investigate the association of subjective sleep characteristics and plasma Alzheimer's disease (AD) biomarkers in older cognitively unimpaired adults with higher amyloid-β (Aβ) burden. Unimpaired cognition was determined by education-adjusted performance for the Mini-Mental State Examination and exclusion of dementia and mild cognitive impairment via standardized neuropsychological tests. We used Pittsburgh Sleep Quality Index (PSQI) to assess subjective sleep quality. The participants also underwent examination of plasma AD biomarkers and

Indexed as

Alzheimer DiseaseCognitive DysfunctionAdultAgedAmyloid beta-PeptidesBiomarkersCognitionHumansPositron-Emission TomographySleeptau ProteinsAmyloid beta-PeptidesBiomarkerstau Proteins18F-florbetapir PETAlzheimer’s diseaseOlder cognitively unimpaired adultsPlasma biomarkersSleep

Identifiers

PMID36806992
OpenAlexW4321478226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.