SynthesisThe journal of nutrition, health & aging2023
Prevalence and Risk Factors of Frailty in Stroke Patients: A Meta-Analysis and Systematic Review.
Synthesis in The journal of nutrition, health & aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Interplay between frailty and cardiometabolic disorders: from pathophysiology to clinical implications.Cardiovascular diabetology · 2025Pooled it
- Association between pre-stroke frailty status and stroke risk and impact on outcomes: a systematic review and meta-analysis of 1,660,328 participants.Aging clinical and experimental research · 2024Pooled it
- Risk factors for preoperative frailty in older patients with gastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Role of frailty in predicting outcomes after stroke: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Prevalence of cognitive frailty in older adults with stroke in China: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Risk prediction models for frailty in stroke patients: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Changes in Frailty, Depression, and Loneliness among Stroke Survivors and Their Spouses.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Unraveling 'F' factor: towards a genetic-clinical framework for the musculoskeletal-heart crosstalk in metabolic aging.Cardiovascular diabetology · 2026Article
- The Relationship Between Brain Frailty and Physical Function in Patients With Stroke Undergoing Rehabilitation.Cureus · 2025Article
- Impact of impaired intrinsic capacity on postoperative frailty in elderly patients undergoing colorectal surgery: study protocol for a single-center, prospective, cohort study.Frontiers in aging neuroscience · 2025Article
- Multidimensional Analysis of Frailty and Its Influencing Factors in Hospitalized Elderly Stroke Patients.Clinical interventions in aging · 2025Article
- Development and validation of a model to predict the risk of frailty in older adults with panvascular disease.Frontiers in public health · 2025Article
- Cardiometabolic multimorbidity and frailty in middle-aged and older adults: a cross-nationally harmonized study.Frontiers in public health · 2025Article
- Cross-sectional association between hs-CRP/HDL-C ratio and physical frailty among middle-aged and older adults: findings from a population-based study.Frontiers in public health · 2025Article
- Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis.Journal of family medicine and primary care · 2024Review
- Pragmatic solutions for the global burden of stroke - Authors' reply.The Lancet. Neurology · 2024Article
- An Age-Stratified Cross-Sectional Study of Physical Activity and Exercise Adherence of Stroke Survivors in Rural Regions.Patient preference and adherence · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSummarize the existing evidence regarding the prevalence and risk factors of frailty in stroke patients.
designA meta-analysis and systematic review.
participantsStroke patients in hospitals or communities.
methodsWe undertook a systematic review and meta-analysis using articles available in 8 databases, including PubMed, The Cochrane Library, Web of Science, Embase, Chinese Biomedical Database (CBM), China National Knowledge Infrastructure Database (CNKI), Wanfang Database, and Weipu Database (VIP) from January 1990 to April 2022. Studies were quality rated using the Newcastle-Ottawa Scale and Agency for Healthcare Research and Quality tool.
resultsA total of 24 studies involving 30,423 participants were identified. The prevalence of frailty and pre-frailty in stroke patients was 27% (95%CI: 0.23-0.31) and 47.9% (95%CI: 0.43-0.53). Female gender (OR = 1.76, 95%CI: 1.63-1.91), advanced age (MD = 6.73, 95%CI: 3.55-9.91), diabetes (OR = 1.34, 95%CI: 1.06-1.69), hyperlipidemia (OR = 1.46, 95%CI: 1.04-2.04), atrial fibrillation (OR = 1.36, 95%CI: 1.01-1.82), National Institutes of Stroke Scale (NIHSS) admission scores (MD = 2.27, 95%CI: 1.72-2.81) were risk factors of frailty in stroke patients.
conclusionsFrailty was more prevalent in stroke patients. Female gender, advanced age, diabetes, hyperlipidemia, atrial fibrillation, and National Institutes of Stroke Scale (NIHSS) admission scores were identified as risk factors for frailty in stroke patients. In the future, medical staff should pay attention to the early screening of frailty in high-risk groups and provide information on its prevention.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.