Evidence map›Paper›PMID 36806801›Full record

ReviewNature cancer2023

Advances in antibody-based therapy in oncology.

Sacha Zinn, Rodrigo Vazquez-Lombardi, Carsten Zimmermann, Puja Sapra, Lutz Jermutus, Daniel Christ

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Targeting CD24 Activates Macrophages to Reduce Tumor Burden in Preclinical Models of Solid Tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Biologics for cardiovascular diseases: from bench to bedside.Signal transduction and targeted therapy · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  19. Review
  20. Review

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sacha ZinnGarvan Institute of Medical Research, Sydney, New South Wales, Australia.
Rodrigo Vazquez-LombardiGarvan Institute of Medical Research, Sydney, New South Wales, Australia.
Carsten ZimmermannUniversity of San Diego, Knauss School of Business, San Diego, CA, USA.
Puja SapraAstraZeneca, Oncology R&D, Biologics Engineering & Targeted Delivery, Gaithersburg, MD, USA.
Lutz JermutusAstraZeneca, BioPharmaceuticals R&D, Research & Early Development, Cambridge, UK.ORCID http://orcid.org/0000-0001-7660-8467
Daniel ChristGarvan Institute of Medical Research, Sydney, New South Wales, Australia. d.christ@garvan.org.au.ORCID http://orcid.org/0000-0002-7313-3977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoclonal antibodies are a growing class of targeted cancer therapeutics, characterized by exquisite specificity, long serum half-life, high affinity and immune effector functions. In this review, we outline key advances in the field with a particular focus on recent and emerging classes of engineered antibody therapeutic candidates, discuss molecular structure and mechanisms of action and provide updates on clinical development and practice.

Indexed as

Antibodies, MonoclonalNeoplasmsHumansRadioimmunotherapyAntibodies, Monoclonal

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.