ReviewPediatric surgery international2023
Endoscopic injection of bulking agents in pediatric vesicoureteral reflux: a narrative review of the literature.
Review in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Short- and long-term outcomes of Deflux injection versus ureteral reimplantation in pediatric vesicoureteral reflux: a narrative review.Annals of medicine and surgery (2012) · 2026Review
- Refining Robotic Extravesical Ureteral Reimplantation: Impact of Ureteral Adventitia Inclusion and Distal-First Detrusorraphy.Journal of clinical medicine · 2026Article
- Long-Term Bladder Dysfunction and Bilateral Obstructive Megaureter in VACTERL Syndrome: A Case Report of Challenging Urological Management.Reports (MDPI) · 2025Article
- Article
- Attaining competency and proficiency in pediatric robot-assisted laparoscopic ureteric reimplantation: a learning curve configuration using cumulative sum analysis.World journal of urology · 2025Article
- Acute kidney injury caused by ureteral obstruction after DefluxBMC urology · 2025Article
- What paediatricians need to know about modern urologic management of vesicoureteral reflux.Frontiers in pediatrics · 2025Review
- Primary vesicoureteral reflux.Nature reviews. Disease primers · 2024Review
- Unraveling the Veil: Deflux Injection Masquerading as Calculus at the Vesicoureteric Junction.The Indian journal of radiology & imaging · 2024Article
- Robot-Assisted Extravesical Ureteral Reimplantation (REVUR) in Pediatric Patients: A New Standard of Treatment for Patients with VUR-A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Validation of A 3D-printed simulator for training in endoscopic injection of bulking agent for vesicoureteral reflux: a pilot study.Surgical endoscopy · 2024Article
- Recurrence of vesico-ureteral reflux in children: is still the endoscopic injection the best option?Translational andrology and urology · 2024Article
- Efficacy of Three Different Injection Techniques for the Endoscopic Treatment of Vesicoureteral Reflux (VUR) in Children: A Review of 10 Years of Experience.Research and reports in urology · 2024Article
- Therapeutic Management of Children with Vesicoureteral Reflux.Journal of clinical medicine · 2023Article
- Efficacy and safety of Hyadex for treatment of vesicoureteral reflux: a multicenter experience.The Journal of international medical research · 2023Observational
- Letter to editors regarding "Escolino et al.: endoscopic injection of bulking agents in pediatric vesicoureteral reflux: a narrative review of literature. Pediatr Surg Int 39: 133".Pediatric surgery international · 2023Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last 20 years, endoscopic injection (EI) has affirmed as a valid alternative to open surgery for management of pediatric vesicoureteral reflux (VUR). This study aimed to investigate and discuss some debated aspects such as indications, bulking agents and comparison, techniques of injection and comparison, predictive factors of success, use in specific situations. EI is minimally invasive, well accepted by patients and families, with short learning curve and low-morbidity profile. It provides reflux resolution rates approaching those of open reimplantation, ranging from 69 to 100%. Obviously, the success rate may be influenced by several factors. Recently, it is adopted as first-line therapy also in high grade reflux or complex anatomy such as duplex, bladder diverticula, ectopic ureters. The two most used materials for injection are Deflux and Vantris. The first is absorbable, easier to inject, has lower risk of obstruction, but can lose efficacy over time. The second is non-absorbable, more difficult to inject, has higher risk of obstruction, but it is potentially more durable. The two main techniques are STING and HIT. To date, the ideal material and technique of injection has not yet clearly established, but the choice remains dependent on surgeon's preference and experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.