Evidence map›Paper›PMID 36806699›Full record

ReviewStem cells translational medicine2023

Combining Cell Technologies With Biomimetic Tissue Engineering Applications: A New Paradigm for Translational Cardiovascular Therapies.

Sarah E Motta, Marcy Martin, Eric K N Gähwiler, Valery L Visser, Polina Zaytseva, Arian Ehterami, Simon P Hoerstrup, Maximilian Y Emmert

Abstract readReview
In one paragraph

Review in Stem cells translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah E MottaInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.ORCID 0000-0001-9056-3365
Marcy MartinInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.
Eric K N GähwilerInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.
Valery L VisserInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.
Polina ZaytsevaInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.
Arian EhteramiInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.
Simon P HoerstrupInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.
Maximilian Y EmmertInstitute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is a major cause of morbidity and mortality worldwide and, to date, the clinically available prostheses still present several limitations. The design of next-generation regenerative replacements either based on cellular or extracellular matrix technologies can address these shortcomings. Therefore, tissue engineered constructs could potentially become a promising alterative to the current therapeutic options for patients with cardiovascular diseases. In this review, we selectively present an overview of the current tissue engineering tools such as induced pluripotent stem cells, biomimetic materials, computational modeling, and additive manufacturing technologies, with a focus on their application to translational cardiovascular therapies. We discuss how these advanced technologies can help the development of biomimetic tissue engineered constructs and we finally summarize the latest clinical evidence for their use, and their potential therapeutic outcome.

Indexed as

Cardiovascular DiseasesInduced Pluripotent Stem CellsBiomimeticsExtracellular MatrixHumansTissue Engineeringadditive manufacturingcomputational modelinghuman pluripotent stem cellstissue engineering

Identifiers

PMID36806699
PMCPMC9985110

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.