Evidence map›Paper›PMID 36806568›Full record

ArticleEuropean radiology2023

CT colonography: can we achieve an adequate bowel preparation without diet restriction?

Marco Rengo, Filippo Tiberia, Simone Vicini, Davide Bellini, Michela Celestre, Gianfranco Trionfera, Andrea Laghi, Iacopo Carbone

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marco RengoDepartment of Medico-Surgical Sciences and Biotechnologies, Academic Diagnostic Imaging Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana, 1668, 04100, Latina, Italy. marco.rengo@uniroma1.it.ORCID http://orcid.org/0000-0001-9087-5692
Filippo TiberiaDepartment of Radiological, Oncological and Pathological Sciences, Academic Diagnostic Imaging Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana, 1668, 04100, Latina, Italy.
Simone ViciniDepartment of Radiological, Oncological and Pathological Sciences, Academic Diagnostic Imaging Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana, 1668, 04100, Latina, Italy.
Davide BelliniDepartment of Medico-Surgical Sciences and Biotechnologies, Academic Diagnostic Imaging Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana, 1668, 04100, Latina, Italy.
Michela CelestreDiagnostic Imaging Unit, Valmontone Hospital, Via Dei Lecci, Valmontone, RM, Italy.
Gianfranco TrionferaDiagnostic Imaging Unit, Valmontone Hospital, Via Dei Lecci, Valmontone, RM, Italy.
Andrea LaghiDepartment of Surgical and Medical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, "Sapienza" University of Rome, Via Di Grottarossa 1035, 00189, Rome, Italy.
Iacopo CarboneDepartment of Radiological, Oncological and Pathological Sciences, Academic Diagnostic Imaging Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana, 1668, 04100, Latina, Italy.
Sapienza University of Rome · ITValmontone Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate if an adequate bowel preparation for CT colonography, can be achieved without diet restriction, using a reduced amount of cathartic agent and fecal tagging. To investigate the influence of patients' characteristics on bowel preparation and the impact on patients' compliance.

methodsIn total, 1446 outpatients scheduled for elective CT colonography were prospectively enrolled. All patients had the same bowel preparation based on a reduced amount of cathartic agent (120 g of macrogol in 1.5 l of water) the day before the exam and a fecal tagging agent (60 ml of hyperosmolar oral iodinated agent) the day of the exam. No dietary restrictions were imposed before the exam. The bowel preparation was evaluated using a qualitative and quantitative score. Patients were grouped by age, gender, and presence of diverticula in both scores. Patients' compliance has been evaluated with a questionnaire after the end of the exam and with a phone-calling interview the day after the exam.

resultsAccording to the qualitative score, adequate bowel preparation was achieved in 1349 patients (93.29%) and no statistical differences were observed among the subgroups of patients. Quantitative scores demonstrated that colon distension was significantly better in younger patients and without diverticula. A good patients' compliance was observed and most patients (96.5%) were willing to repeat it.

conclusionsThe lack of diet restriction does not affect the quality of CTC preparation and good patient's compliance could potentially increase the participation rate in CRC screening programs. KEY POINTS: • An adequate quality bowel preparation for CT colonography can be achieved without diet restriction, using a reduced amount of cathartic agent (120 g of macrogol in 1.5 l of water) and fecal tagging (60 ml of hyperosmolar oral iodinated agent). • A bowel preparation based on the combination of a reduced amount of cathartic agent and fecal tagging, without diet restriction, allows obtaining good quality in more than 90% of patients. • The bowel preparation scheme proposed reduces the distress and discomfort experienced by the patients improving adherence to CTC.

Indexed as

CatharticsColonography, Computed TomographicContrast MediaDietFecesHumansPolyethylene GlycolsCatharticsContrast MediaPolyethylene GlycolsBowel preparation solutionColonography, computed tomographicDietPatient compliance

Identifiers

PMID36806568
PMCPMC10289920
OpenAlexW4321352043

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.